Effect of model parameters on phage lysis plaque expansion.
<p>Phage lysis plaque radius r expansion kinetics (main panels) are obtained by integration of velocity changes over time (insets). The velocity scaling factor δβ is kept constant at value 1.0 (Eq. 18). <b>(a, b)</b> <i>Effect of cell morphological parameters.</i> Chang...
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2025
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| _version_ | 1851482315178377216 |
|---|---|
| author | Julián Bulssico (16979655) |
| author2 | Swapnesh Panigrahi (400344) Mélanie Matveeva (22367417) Nicolas Ginet (253310) Mireille Ansaldi (207607) |
| author2_role | author author author author |
| author_facet | Julián Bulssico (16979655) Swapnesh Panigrahi (400344) Mélanie Matveeva (22367417) Nicolas Ginet (253310) Mireille Ansaldi (207607) |
| author_role | author |
| dc.creator.none.fl_str_mv | Julián Bulssico (16979655) Swapnesh Panigrahi (400344) Mélanie Matveeva (22367417) Nicolas Ginet (253310) Mireille Ansaldi (207607) |
| dc.date.none.fl_str_mv | 2025-10-03T17:36:06Z |
| dc.identifier.none.fl_str_mv | 10.1371/journal.ppat.1013546.s004 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/figure/Effect_of_model_parameters_on_phage_lysis_plaque_expansion_/30275144 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biophysics Medicine Microbiology Cell Biology Pharmacology Biotechnology Evolutionary Biology Ecology Infectious Diseases Virology Biological Sciences not elsewhere classified key factor leading experiencing renewed interest immobilized bacterial hosts comprehensive model integrating better bacterial eradication cell bloating ). since plaque formation phage therapeutic applications sublethal antibiotic concentrations previous experimental work larger lysis plaques also parameters related two different phages host growth dynamics plaque size observed antibiotics enable phages phage infection parameters div >< p plaque formation lysis plaques host growth bacterial host mathematical model different ways cell morphology cell filamentation host ’ phage therapy phage predation phage infection called phage successive cycles strongly influenced solid media single point research focuses propagation matrix pas ), morphological changes mg1655 infection investigate pas enhanced adsorption efficient predation distinctive manifestation crucial importance compassionate treatments common practice combined administration coli </ circular thinning |
| dc.title.none.fl_str_mv | Effect of model parameters on phage lysis plaque expansion. |
| dc.type.none.fl_str_mv | Image Figure info:eu-repo/semantics/publishedVersion image |
| description | <p>Phage lysis plaque radius r expansion kinetics (main panels) are obtained by integration of velocity changes over time (insets). The velocity scaling factor δβ is kept constant at value 1.0 (Eq. 18). <b>(a, b)</b> <i>Effect of cell morphological parameters.</i> Changing cell length l (<b>a</b>) and cell width w (<b>b</b>). <b>(c, d)</b> <i>Effect of phage parameters.</i> Changing phage adsorption (<b>c</b>) and phage inactivation (<b>d</b>). <b>(e, f)</b> <i>Effect of external parameters.</i> Changing biomass growth rate (<b>e</b>) and biomass capacity Vmax (<b>f</b>).</p> <p>(PNG)</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_c8ac63a4c2fdcc34e4b9d11cec6979b0 |
| identifier_str_mv | 10.1371/journal.ppat.1013546.s004 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/30275144 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Effect of model parameters on phage lysis plaque expansion.Julián Bulssico (16979655)Swapnesh Panigrahi (400344)Mélanie Matveeva (22367417)Nicolas Ginet (253310)Mireille Ansaldi (207607)BiophysicsMedicineMicrobiologyCell BiologyPharmacologyBiotechnologyEvolutionary BiologyEcologyInfectious DiseasesVirologyBiological Sciences not elsewhere classifiedkey factor leadingexperiencing renewed interestimmobilized bacterial hostscomprehensive model integratingbetter bacterial eradicationcell bloating ).since plaque formationphage therapeutic applicationssublethal antibiotic concentrationsprevious experimental worklarger lysis plaquesalso parameters relatedtwo different phageshost growth dynamicsplaque size observedantibiotics enable phagesphage infection parametersdiv >< pplaque formationlysis plaqueshost growthbacterial hostmathematical modeldifferent wayscell morphologycell filamentationhost ’phage therapyphage predationphage infectioncalled phagesuccessive cyclesstrongly influencedsolid mediasingle pointresearch focusespropagation matrixpas ),morphological changesmg1655 infectioninvestigate pasenhanced adsorptionefficient predationdistinctive manifestationcrucial importancecompassionate treatmentscommon practicecombined administrationcoli </circular thinning<p>Phage lysis plaque radius r expansion kinetics (main panels) are obtained by integration of velocity changes over time (insets). The velocity scaling factor δβ is kept constant at value 1.0 (Eq. 18). <b>(a, b)</b> <i>Effect of cell morphological parameters.</i> Changing cell length l (<b>a</b>) and cell width w (<b>b</b>). <b>(c, d)</b> <i>Effect of phage parameters.</i> Changing phage adsorption (<b>c</b>) and phage inactivation (<b>d</b>). <b>(e, f)</b> <i>Effect of external parameters.</i> Changing biomass growth rate (<b>e</b>) and biomass capacity Vmax (<b>f</b>).</p> <p>(PNG)</p>2025-10-03T17:36:06ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1371/journal.ppat.1013546.s004https://figshare.com/articles/figure/Effect_of_model_parameters_on_phage_lysis_plaque_expansion_/30275144CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/302751442025-10-03T17:36:06Z |
| spellingShingle | Effect of model parameters on phage lysis plaque expansion. Julián Bulssico (16979655) Biophysics Medicine Microbiology Cell Biology Pharmacology Biotechnology Evolutionary Biology Ecology Infectious Diseases Virology Biological Sciences not elsewhere classified key factor leading experiencing renewed interest immobilized bacterial hosts comprehensive model integrating better bacterial eradication cell bloating ). since plaque formation phage therapeutic applications sublethal antibiotic concentrations previous experimental work larger lysis plaques also parameters related two different phages host growth dynamics plaque size observed antibiotics enable phages phage infection parameters div >< p plaque formation lysis plaques host growth bacterial host mathematical model different ways cell morphology cell filamentation host ’ phage therapy phage predation phage infection called phage successive cycles strongly influenced solid media single point research focuses propagation matrix pas ), morphological changes mg1655 infection investigate pas enhanced adsorption efficient predation distinctive manifestation crucial importance compassionate treatments common practice combined administration coli </ circular thinning |
| status_str | publishedVersion |
| title | Effect of model parameters on phage lysis plaque expansion. |
| title_full | Effect of model parameters on phage lysis plaque expansion. |
| title_fullStr | Effect of model parameters on phage lysis plaque expansion. |
| title_full_unstemmed | Effect of model parameters on phage lysis plaque expansion. |
| title_short | Effect of model parameters on phage lysis plaque expansion. |
| title_sort | Effect of model parameters on phage lysis plaque expansion. |
| topic | Biophysics Medicine Microbiology Cell Biology Pharmacology Biotechnology Evolutionary Biology Ecology Infectious Diseases Virology Biological Sciences not elsewhere classified key factor leading experiencing renewed interest immobilized bacterial hosts comprehensive model integrating better bacterial eradication cell bloating ). since plaque formation phage therapeutic applications sublethal antibiotic concentrations previous experimental work larger lysis plaques also parameters related two different phages host growth dynamics plaque size observed antibiotics enable phages phage infection parameters div >< p plaque formation lysis plaques host growth bacterial host mathematical model different ways cell morphology cell filamentation host ’ phage therapy phage predation phage infection called phage successive cycles strongly influenced solid media single point research focuses propagation matrix pas ), morphological changes mg1655 infection investigate pas enhanced adsorption efficient predation distinctive manifestation crucial importance compassionate treatments common practice combined administration coli </ circular thinning |