Cluster distance and size for AC STORM data.

(A) one sample of AC STORM data and the distribution of the cluster distance and size for a 10μm × 10μm region. (i) One sample of AC STORM data. (ii) The magnified plot of the region in the red box in (i). Each red circle labels one cluster: the center...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Lingxia Qiao (19996756) (author)
مؤلفون آخرون:	Michael Getz (17692612) (author), Ben Gross (2993145) (author), Brian Tenner (138904) (author), Jin Zhang (53297) (author), Padmini Rangamani (4740435) (author)
منشور في:	2024
الموضوعات:	Biophysics Biochemistry Microbiology Cell Biology Genetics Neuroscience Physiology Immunology Cancer Science Policy Biological Sciences not elsewhere classified previous experimental studies key circuit motif incoherent feedforward loop develop computational models adenylyl cyclase 8 two important predictions many cellular functions arbitrary phase difference div >< p camp peak simultaneously 2 +</ sup ac nanodomain formation phase oscillations associated enzymes associated two nanodomains ac nanodomains volume ratio turing pattern time delay spatiotemporal orchestration spatial compartmentation signaling molecules second messengers nanoscale organization low level governs camp give rise findings unveil ensuring compartmentation compartment size cellular surface camp oscillations
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الوصف
الملخص:	<p>(A) one sample of AC STORM data and the distribution of the cluster distance and size for a 10<i>μm</i> × 10<i>μm</i> region. (i) One sample of AC STORM data. (ii) The magnified plot of the region in the red box in (i). Each red circle labels one cluster: the center of the circle is calculated from the mean-shift algorithm [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1012564#pcbi.1012564.ref122" target="_blank">122</a>, <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1012564#pcbi.1012564.ref123" target="_blank">123</a>], and the radius of the circle is defined as the value such that the circle can include 95% points of a specific cluster. (iii) The histogram of nearest-neighbor distances in (ii). The mean of the nearest-neighbor distances is indicated in the upper right corner. (iv) The histogram of cluster sizes. The cluster size is defined as the radius of red circles in (ii). The mean cluster size is indicated in the upper right corner. (B-C) Same plot as (A) but for another AC STORM data sample.</p> <p>(EPS)</p>

Cluster distance and size for AC STORM data.

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