Increased selectivity requires competition and nonlinear activation function in pyramidal cells.

<p><b>A)</b> Illustration of the circuit model. Light gray triangles denote excitatory pyramidal populations, circles denote inhibitory populations. Excitatory populations inhibit each other via local interneurons (dark gray) and receive additional inhibition from PV cells (red). T...

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Main Author:	Lilia Kukovska (22683586) (author)
Other Authors:	Katharina A. Wilmes (22683589) (author), Natsumi Y. Homma (22683592) (author), Claudia Clopath (324706) (author), Jasper Poort (22683595) (author)
Published:	2025
Subjects:	Biochemistry Neuroscience Developmental Biology Science Policy Mental Health Biological Sciences not elsewhere classified xlink "> inhibition three major factors strong competitive interactions photon imaging showed balanced cortical activity primary visual cortex sustained v1 activity combined optogenetic activation v1 cells captured moderate pv activation moderate activation visual discriminations expressing cells nonlinear activation dependent activation activation strength task difficulty stimulus onset perceptual discrimination difficult discriminations delineates conditions circuit model behavioral effects
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Increased selectivity requires competition and nonlinear activation function in pyramidal cells.

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