(related to Fig 3) No behavioral improvements in difficult discriminations by extending the early window beyond 120 ms.

(related to Fig 3) No behavioral improvements in difficult discriminations by extending the early window beyond 120 ms.

<p><b>A)</b> Normalized average discrimination performance, <i>d’</i>, <b>B)</b> hit rate, and <b>C)</b> false alarm rate as a function of laser power for the original (0–120 ms) and two new (0–180 ms and 0–340 ms) ‘early’ windows (<i>N<...

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Détails bibliographiques
Auteur principal: Lilia Kukovska (22683586) (author)
Autres auteurs: Katharina A. Wilmes (22683589) (author), Natsumi Y. Homma (22683592) (author), Claudia Clopath (324706) (author), Jasper Poort (22683595) (author)
Publié: 2025
Sujets:
Biochemistry
Neuroscience
Developmental Biology
Science Policy
Mental Health
Biological Sciences not elsewhere classified
xlink "> inhibition
three major factors
strong competitive interactions
photon imaging showed
balanced cortical activity
primary visual cortex
sustained v1 activity
combined optogenetic activation
v1 cells captured
moderate pv activation
moderate activation
visual discriminations
expressing cells
nonlinear activation
dependent activation
activation strength
task difficulty
stimulus onset
perceptual discrimination
difficult discriminations
delineates conditions
circuit model
behavioral effects
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Résumé:<p><b>A)</b> Normalized average discrimination performance, <i>d’</i>, <b>B)</b> hit rate, and <b>C)</b> false alarm rate as a function of laser power for the original (0–120 ms) and two new (0–180 ms and 0–340 ms) ‘early’ windows (<i>N</i> = 4 sessions). Data is normalized by subtracting the value of the 0 power level (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003518#sec015" target="_blank">Methods</a>). Shading, 95% CI of bootstrap distribution.</p> <p>(TIFF)</p>

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