Growth curve of <i>M. smegmatis</i> PLJR962-eccD3-gRNA strain with linezolid and rifampicin.

Growth curve of <i>M. smegmatis</i> PLJR962-eccD3-gRNA strain with linezolid and rifampicin.

<p>Growth curves of <i>M. smegmatis mc</i><sup><i>2</i></sup> 155 wild type strain (diamonds, inner graph a and b), <i>M. smegmatis</i> PLJR962-<i>eccD3</i>-gRNA strain (circles) (a) and (b) without (gray line) and with (black line) A...

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Main Author: Ana Laura Granados-Tristán (21144439) (author)
Other Authors: Mauricio Carrillo-Tripp (3183507) (author), Carlos Eduardo Hernández-Luna (21144442) (author), Aldo Herrera-Rodulfo (21144445) (author), Laura Adiene González-Escalante (8890166) (author), Ana Leticia Arriaga-Guerrero (8890154) (author), Beatriz Silva-Ramírez (8890169) (author), Brenda Leticia Escobedo-Guajardo (18809428) (author), Roberto Mercado-Hernández (8890172) (author), Mario Bermúdez de León (21144448) (author), Katia Peñuelas-Urquides (11639896) (author)
Published: 2025
Subjects:
Biophysics
Biochemistry
Medicine
Microbiology
Molecular Biology
Pharmacology
Biotechnology
Cancer
Infectious Diseases
Biological Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
inhibited using crispri
3 secretion system
favorable δg values
tertiary protein structures
new therapeutic targets
eccd3 dimer interfaces
div >< p
mycolicibacterium smegmatis </
mycobacterium tuberculosis </
ivermectin susceptibility increased
mycobacterium susceptibility
smegmatis </
tuberculosis </
new drugs
molecular structures
ivermectin targets
eccd3 protein
eccd3 increased
best δg
resistant tuberculosis
vitro </
silico </
eccd3 </
zinc homeostasis
quaternary interface
prospective drugs
predicted based
preclinical studies
ivermectin action
compensatory mechanisms
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