Fig 2 -

Dynamics of HBV infection in patients treated with PEG IFN-α: Representative decay characteristics are shown for extracellular HBV DNA, HBsAg, and HBcrAg in peripheral blood of (A) HBeAg-positive patients treated with PEG IFN-α with VR or non-VR, <b&...

وصف كامل

محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Kwang Su Kim (1960972) (author)
مؤلفون آخرون:	Masashi Iwamoto (1399939) (author), Kosaku Kitagawa (9187891) (author), Hyeongki Park (15990598) (author), Sanae Hayashi (18137380) (author), Senko Tsukuda (1399942) (author), Takeshi Matsui (1952263) (author), Masanori Atsukawa (6166814) (author), Kentaro Matsuura (156545) (author), Natthaya Chuaypen (6726911) (author), Pisit Tangkijvanich (513614) (author), Lena Allweiss (366520) (author), Takara Nishiyama (18137383) (author), Naotoshi Nakamura (12083048) (author), Yasuhisa Fujita (10344689) (author), Eiryo Kawakami (750118) (author), Shinji Nakaoka (3326025) (author), Masamichi Muramatsu (407159) (author), Kazuyuki Aihara (44090) (author), Takaji Wakita (109321) (author), Alan S. Perelson (7832039) (author), Maura Dandri (560334) (author), Koichi Watashi (222543) (author), Shingo Iwami (266092) (author), Yasuhito Tanaka (39138) (author)
منشور في:	2025
الموضوعات:	Medicine Cell Biology Cancer Infectious Diseases Virology Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified Chemical Sciences not elsewhere classified xlink "> quantification method combining classic intercellular viral propagation hepatitis b virus extracellular viral markers paired liver biopsy hepatitis b patients although hbv rna evaluating cccdna activity liver biopsy surrogate markers well correlated related antigens quantified cccdna peripheral blood necessarily estimate infected patients including hbsag hbv dna hbv core
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الوصف
الملخص:	<p><b>Dynamics of HBV infection in patients treated with PEG IFN-α:</b> Representative decay characteristics are shown for extracellular HBV DNA, HBsAg, and HBcrAg in peripheral blood of <b>(A)</b> HBeAg-positive patients treated with PEG IFN-α with VR or non-VR, <b>(B)</b> HBeAg-negative patients treated with PEG IFN-α with PVR or non-PVR, and HBeAg-negative patients treated with PEG IFN-α and ETV with PVR or non-PVR, and <b>(C)</b> patients treated with ETV or LAM. <b>(D)</b> The distributions of the half-life of cccDNA before and after treatment with PEG IFN-α (+ETV or LAM) for HBeAg-positive/negative and (P)VR/non-(P)VR patients are shown. <b>(E)</b> Estimated half-life of cccDNA in hepatocyte from patients with IL28B CC (n = 208) or CT (n = 18) genotype treated with PEG IFN-α are shown. Black line indicates the median; box and whiskers show the interquartile range (IQR) and 1.5xIQR, respectively.</p>

Fig 2 -

مواد مشابهة