Additional data from murine infection experiments.

<p>A. Kaplan-Meier survival curves of mice infected with 1.25x10<sup>6</sup> bacteria per animal and monitored for 12 days (low dose experiment). Only strain Kato caused lethality at this dose. Statistical significance was determined using log-rank Mantel-Cox analysis.</p> &l...

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Bibliographic Details
Main Author:	Panjaporn Chaichana (538714) (author)
Other Authors:	Naphat Satapoomin (9972578) (author), Chitrasak Kullapanich (11036895) (author), Suthida Chuenklin (21627534) (author), Aisha Mohammad (10841586) (author), Manutsanun Inthawong (13199766) (author), Erin E. Ball (13002065) (author), Thomas P. Burke (21627537) (author), Piyanate Sunyakumthorn (288420) (author), Jeanne Salje (789501) (author)
Published:	2025
Subjects:	Medicine Microbiology Evolutionary Biology Ecology Immunology Infectious Diseases Virology Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified surface protein scac severe scrub typhus epidemiological human data effector proteins encoded model whereby drivers induced higher levels virulence factors responsible observed differential virulence fully avirulent strain extensive strain diversity seven diverse strains comparative virulence analysis orientia tsutsugamushi </ tsutsugamushi </ increased levels based analysis bacterial drivers relative virulence vitro </ leptotrombidium </ yet differences well understood well defined virulent strains varying arsenal subcellular localisation single gene mechanistic basis leads us host cells growth rate growth properties gene group distributed throughout distinguishing feature different strains complex ways complex interplay clear pattern chemokine induction
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Additional data from murine infection experiments.

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