M7G regulators may improve oxidative phosphorylation in brain cells of epilepsy.
<p>(A) Differentially expressed genes related to oxidative phosphorylation between gene clusters. (B) M7G scores of TLE patients’ brain cells, TLE1 with higher scores than others. (C-H) Expression of oxidative phosphorylation related genes in each TLE patients’ brain cells, including 6 parts,...
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| المؤلف الرئيسي: | |
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| مؤلفون آخرون: | , , , , , |
| منشور في: |
2025
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| الموضوعات: | |
| الوسوم: |
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| _version_ | 1852018497986494464 |
|---|---|
| author | Jiangli Zhao (2308330) |
| author2 | Qingyuan Sun (188592) Xuchen Liu (13258842) Jiwei Wang (508674) Ning Yang (114965) Chao Li (145513) Xinyu Wang (341591) |
| author2_role | author author author author author author |
| author_facet | Jiangli Zhao (2308330) Qingyuan Sun (188592) Xuchen Liu (13258842) Jiwei Wang (508674) Ning Yang (114965) Chao Li (145513) Xinyu Wang (341591) |
| author_role | author |
| dc.creator.none.fl_str_mv | Jiangli Zhao (2308330) Qingyuan Sun (188592) Xuchen Liu (13258842) Jiwei Wang (508674) Ning Yang (114965) Chao Li (145513) Xinyu Wang (341591) |
| dc.date.none.fl_str_mv | 2025-07-14T17:30:34Z |
| dc.identifier.none.fl_str_mv | 10.1371/journal.pone.0327256.s005 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/figure/M7G_regulators_may_improve_oxidative_phosphorylation_in_brain_cells_of_epilepsy_/29563539 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biochemistry Microbiology Cell Biology Molecular Biology Neuroscience Immunology Mental Health Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified sup >+</ sup nearly 1 %. machine learning algorithms gene expression analysis common brain disease causes different types attracted significant attention prevalent rna modification immune cell infiltration neuronal oxidative phosphorylation findings also suggested div >< p rna expression levels identified m7g regulators epilepsy patients confirmed oxidative phosphorylation m7g regulators immune microenvironment epilepsy patients rna n7 two subtypes tissue samples regulatory pattern recent research programmed death nomogram model m7g patterns m7g methylation integrative role insights gained incidence rate important role healthy controls datasets gse143272 cytolytic activity constructed based consensus clustering clinical significance cellular death |
| dc.title.none.fl_str_mv | M7G regulators may improve oxidative phosphorylation in brain cells of epilepsy. |
| dc.type.none.fl_str_mv | Image Figure info:eu-repo/semantics/publishedVersion image |
| description | <p>(A) Differentially expressed genes related to oxidative phosphorylation between gene clusters. (B) M7G scores of TLE patients’ brain cells, TLE1 with higher scores than others. (C-H) Expression of oxidative phosphorylation related genes in each TLE patients’ brain cells, including 6 parts, which are NADH Dehydrogenase (C), Cytochrome C Reductase (D), Cytochrome C Oxidase (E), Succinate Dehydrogenase (F), Cytochrome C (G), and V-type ATPase (H). *p < 0.05, **p < 0.01, ***p < 0.001.</p> <p>(PNG)</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_ce0f60c8cb459aee69cf73f602beb4ec |
| identifier_str_mv | 10.1371/journal.pone.0327256.s005 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/29563539 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | M7G regulators may improve oxidative phosphorylation in brain cells of epilepsy.Jiangli Zhao (2308330)Qingyuan Sun (188592)Xuchen Liu (13258842)Jiwei Wang (508674)Ning Yang (114965)Chao Li (145513)Xinyu Wang (341591)BiochemistryMicrobiologyCell BiologyMolecular BiologyNeuroscienceImmunologyMental HealthEnvironmental Sciences not elsewhere classifiedBiological Sciences not elsewhere classifiedsup >+</ supnearly 1 %.machine learning algorithmsgene expression analysiscommon brain diseasecauses different typesattracted significant attentionprevalent rna modificationimmune cell infiltrationneuronal oxidative phosphorylationfindings also suggesteddiv >< prna expression levelsidentified m7g regulatorsepilepsy patients confirmedoxidative phosphorylationm7g regulatorsimmune microenvironmentepilepsy patientsrna n7two subtypestissue samplesregulatory patternrecent researchprogrammed deathnomogram modelm7g patternsm7g methylationintegrative roleinsights gainedincidence rateimportant rolehealthy controlsdatasets gse143272cytolytic activityconstructed basedconsensus clusteringclinical significancecellular death<p>(A) Differentially expressed genes related to oxidative phosphorylation between gene clusters. (B) M7G scores of TLE patients’ brain cells, TLE1 with higher scores than others. (C-H) Expression of oxidative phosphorylation related genes in each TLE patients’ brain cells, including 6 parts, which are NADH Dehydrogenase (C), Cytochrome C Reductase (D), Cytochrome C Oxidase (E), Succinate Dehydrogenase (F), Cytochrome C (G), and V-type ATPase (H). *p < 0.05, **p < 0.01, ***p < 0.001.</p> <p>(PNG)</p>2025-07-14T17:30:34ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1371/journal.pone.0327256.s005https://figshare.com/articles/figure/M7G_regulators_may_improve_oxidative_phosphorylation_in_brain_cells_of_epilepsy_/29563539CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/295635392025-07-14T17:30:34Z |
| spellingShingle | M7G regulators may improve oxidative phosphorylation in brain cells of epilepsy. Jiangli Zhao (2308330) Biochemistry Microbiology Cell Biology Molecular Biology Neuroscience Immunology Mental Health Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified sup >+</ sup nearly 1 %. machine learning algorithms gene expression analysis common brain disease causes different types attracted significant attention prevalent rna modification immune cell infiltration neuronal oxidative phosphorylation findings also suggested div >< p rna expression levels identified m7g regulators epilepsy patients confirmed oxidative phosphorylation m7g regulators immune microenvironment epilepsy patients rna n7 two subtypes tissue samples regulatory pattern recent research programmed death nomogram model m7g patterns m7g methylation integrative role insights gained incidence rate important role healthy controls datasets gse143272 cytolytic activity constructed based consensus clustering clinical significance cellular death |
| status_str | publishedVersion |
| title | M7G regulators may improve oxidative phosphorylation in brain cells of epilepsy. |
| title_full | M7G regulators may improve oxidative phosphorylation in brain cells of epilepsy. |
| title_fullStr | M7G regulators may improve oxidative phosphorylation in brain cells of epilepsy. |
| title_full_unstemmed | M7G regulators may improve oxidative phosphorylation in brain cells of epilepsy. |
| title_short | M7G regulators may improve oxidative phosphorylation in brain cells of epilepsy. |
| title_sort | M7G regulators may improve oxidative phosphorylation in brain cells of epilepsy. |
| topic | Biochemistry Microbiology Cell Biology Molecular Biology Neuroscience Immunology Mental Health Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified sup >+</ sup nearly 1 %. machine learning algorithms gene expression analysis common brain disease causes different types attracted significant attention prevalent rna modification immune cell infiltration neuronal oxidative phosphorylation findings also suggested div >< p rna expression levels identified m7g regulators epilepsy patients confirmed oxidative phosphorylation m7g regulators immune microenvironment epilepsy patients rna n7 two subtypes tissue samples regulatory pattern recent research programmed death nomogram model m7g patterns m7g methylation integrative role insights gained incidence rate important role healthy controls datasets gse143272 cytolytic activity constructed based consensus clustering clinical significance cellular death |