Supplementary Figure S1 from Combined Inactivation of MEK and mTOR Can Lead to Synergistic Cell Death in Glioblastoma Models and Associates with NF1 Deficiency and a Mesenchymal Subtype

Supplementary Figure S1 from Combined Inactivation of MEK and mTOR Can Lead to Synergistic Cell Death in Glioblastoma Models and Associates with NF1 Deficiency and a Mesenchymal Subtype

<p>Supplementary Figure S1: Overview of averaged cell viability (n = 3) of all concentration-titrated combination therapies per cell line.</p>

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Bibliographic Details
Main Author: Fleur M.G. Cornelissen (22761190) (author)
Other Authors: Yoran Broersma (22761193) (author), Ravi S. Narayan (22761196) (author), Rogier Dik (22761199) (author), Sander R. Piersma (22761202) (author), Richard de Goeij-de Haas (22761205) (author), Thang V. Pham (15037293) (author), David Noske (18366693) (author), William P. Vandertop (15037296) (author), Connie R. Jimenez (12057149) (author), Bart A. Westerman (18100116) (author)
Published: 2025
Subjects:
Cancer
Molecular and Cellular Biology
Therapeutic Research and Development
Cell Signaling
Phosphatases
CNS Cancers
Gliomas, Glioblastomas
Drug Resistance
Drug Targets
Metabolism
Metabolic pathways
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