Biological pathway enrichment analysis for key genes identified by the CASynergy algorithm in different cancer cell lines.

Biological pathway enrichment analysis for key genes identified by the CASynergy algorithm in different cancer cell lines.

<p><b>(a)</b> Breast cancer cell line KPL-1. <b>(b)</b> Lung squamous cell carcinoma cell line NCI-H520. <b>(c)</b> Ovarian clear cell carcinoma cell line ES2.</p>

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Haitao Li (305080) (author)
مؤلفون آخرون: Long Zheng (694761) (author), Lei Li (29537) (author), Yiwei Chen (383344) (author), Junjie Li (12724) (author), Chunhou Zheng (15936521) (author), Yansen Su (459998) (author)
منشور في: 2025
الموضوعات:
Biochemistry
Medicine
Genetics
Pharmacology
Biotechnology
Cancer
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Information Systems not elsewhere classified
unique molecular context
improve treatment efficacy
specific molecular interactions
complex biological interactions
attention synergy ),
two benchmark datasets
provides interpretable insights
personalized cancer treatment
causal attention model
causal attention mechanism
improvements allow casynergy
cancer cell line
causal attention
cell line
gene interactions
attention module
multimodal datasets
interpretable prediction
yet suffer
tumor heterogeneity
reliable way
propose casynergy
promising strategy
prior approaches
overcome resistance
inadequate modeling
challenging due
casynergy offers
casynergy introduces
art models
addresses limitations
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