Cryo-EM data processing workflow.

<div><p>[Fe-S] clusters are ancient and ubiquitous protein co-factors, which contributed to the emergence of life in an anoxic planet. We have recently identified two minimal [Fe-S] biogenesis systems, MIS and SMS, inferred to be ancestral systems dating back to the Last Universal Common...

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Bibliographic Details
Main Author:	Macha Dussouchaud (21601445) (author)
Other Authors:	Markel Martinez-Carranza (21601448) (author), Pierre-Simon Garcia (21601451) (author), Martin Clémancey (347878) (author), Geneviève Blondin (2668756) (author), Jean Michel Betton (21601454) (author), Ahmed Haouz (5624486) (author), Simonetta Gribaldo (3252) (author), Sandrine Ollagnier de Choudens (21601457) (author), Ludovic Sauguet (250490) (author), Ariel Mechaly (12131742) (author), Frédéric Barras (207624) (author)
Published:	2025
Subjects:	Biophysics Biochemistry Microbiology Genetics Biotechnology Evolutionary Biology Cancer Infectious Diseases Virology Chemical Sciences not elsewhere classified ubiquitous protein co studied modern iron present study focuses mutually exclusive allowing methanocaldococcus jannaschii </ mechanistic model describing escherichia coli </ contained cys residues bona fide </ anaerobic prokaryotes prior structural studies showed study established sms sms system rescued smsc subunit hosts suf systems grown cluster binding sites cluster assembly site biogenesis system sms biogenesis system biogenesis systems unique structural cluster assembly ancestor sms sulfur cluster unique mechanism similar c regulatory coupling nif ), key role hyperthermophilic archaeon heterotetratmer wherein gave rise functional features anoxic planet anoxic conditions
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Cryo-EM data processing workflow.

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