Figure 6 from Impact of Duration of Neoadjuvant Aromatase Inhibitors on Molecular Expression Profiles in Estrogen Receptor–positive Breast Cancers
<p>Boxplots showing changes in gene expression from baseline to surgery of the two immune-related signatures (“durvalumab” and “immune-tolerance”) among H-H and H-L Ki67 response categories in the POETIC-treated subset (<b>A</b>) and in the NeoAI study (<b>B</b>). Boxpl...
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2025
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| _version_ | 1849927634768625664 |
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| author | Milana A. Bergamino (15038015) |
| author2 | Gabriele Morani (15038018) Joel Parker (15038021) Eugene F. Schuster (9726535) Mariana F. Leal (15038024) Elena López-Knowles (15038027) Holly Tovey (9360536) Judith M. Bliss (8827107) John F.R. Robertson (15025368) Ian E. Smith (1545553) Mitch Dowsett (645) Maggie C.U. Cheang (14946768) |
| author2_role | author author author author author author author author author author author |
| author_facet | Milana A. Bergamino (15038015) Gabriele Morani (15038018) Joel Parker (15038021) Eugene F. Schuster (9726535) Mariana F. Leal (15038024) Elena López-Knowles (15038027) Holly Tovey (9360536) Judith M. Bliss (8827107) John F.R. Robertson (15025368) Ian E. Smith (1545553) Mitch Dowsett (645) Maggie C.U. Cheang (14946768) |
| author_role | author |
| dc.creator.none.fl_str_mv | Milana A. Bergamino (15038015) Gabriele Morani (15038018) Joel Parker (15038021) Eugene F. Schuster (9726535) Mariana F. Leal (15038024) Elena López-Knowles (15038027) Holly Tovey (9360536) Judith M. Bliss (8827107) John F.R. Robertson (15025368) Ian E. Smith (1545553) Mitch Dowsett (645) Maggie C.U. Cheang (14946768) |
| dc.date.none.fl_str_mv | 2025-11-25T12:05:23Z |
| dc.identifier.none.fl_str_mv | 10.1158/1078-0432.30705365 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/figure/Figure_6_from_Impact_of_Duration_of_Neoadjuvant_Aromatase_Inhibitors_on_Molecular_Expression_Profiles_in_Estrogen_Receptor_positive_Breast_Cancers/30705365 |
| dc.rights.none.fl_str_mv | CC BY info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Cancer Tumor Biology Cancer Detection and Diagnosis Therapeutic Research and Development Biomarkers Genetic biomarkers Breast Cancer Drug Resistance Novel mechanisms Endocrinology Translational Research |
| dc.title.none.fl_str_mv | Figure 6 from Impact of Duration of Neoadjuvant Aromatase Inhibitors on Molecular Expression Profiles in Estrogen Receptor–positive Breast Cancers |
| dc.type.none.fl_str_mv | Image Figure info:eu-repo/semantics/publishedVersion image |
| description | <p>Boxplots showing changes in gene expression from baseline to surgery of the two immune-related signatures (“durvalumab” and “immune-tolerance”) among H-H and H-L Ki67 response categories in the POETIC-treated subset (<b>A</b>) and in the NeoAI study (<b>B</b>). Boxplots showing gene signature expression of the two immune-related signatures at surgery stratified by H-H and H-L tumors in the POETIC-treated subset (<b>C</b>) and in the NeoAI study (<b>D</b>). H-H, Ki67 High<sub>baseline</sub>- Ki67 High<sub>surgery</sub>; H-L, Ki67 High<sub>baseline</sub>- Ki67 Low<sub>surgery</sub>; Her2-E, Her2 enriched; LumB, Luminal B; LumA, Luminal A; 2 wk, 2-week time point.</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_d6dab250216902a03e0db0711133e6d1 |
| identifier_str_mv | 10.1158/1078-0432.30705365 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/30705365 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY |
| spelling | Figure 6 from Impact of Duration of Neoadjuvant Aromatase Inhibitors on Molecular Expression Profiles in Estrogen Receptor–positive Breast CancersMilana A. Bergamino (15038015)Gabriele Morani (15038018)Joel Parker (15038021)Eugene F. Schuster (9726535)Mariana F. Leal (15038024)Elena López-Knowles (15038027)Holly Tovey (9360536)Judith M. Bliss (8827107)John F.R. Robertson (15025368)Ian E. Smith (1545553)Mitch Dowsett (645)Maggie C.U. Cheang (14946768)CancerTumor BiologyCancer Detection and DiagnosisTherapeutic Research and DevelopmentBiomarkersGenetic biomarkersBreast CancerDrug ResistanceNovel mechanismsEndocrinologyTranslational Research<p>Boxplots showing changes in gene expression from baseline to surgery of the two immune-related signatures (“durvalumab” and “immune-tolerance”) among H-H and H-L Ki67 response categories in the POETIC-treated subset (<b>A</b>) and in the NeoAI study (<b>B</b>). Boxplots showing gene signature expression of the two immune-related signatures at surgery stratified by H-H and H-L tumors in the POETIC-treated subset (<b>C</b>) and in the NeoAI study (<b>D</b>). H-H, Ki67 High<sub>baseline</sub>- Ki67 High<sub>surgery</sub>; H-L, Ki67 High<sub>baseline</sub>- Ki67 Low<sub>surgery</sub>; Her2-E, Her2 enriched; LumB, Luminal B; LumA, Luminal A; 2 wk, 2-week time point.</p>2025-11-25T12:05:23ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1158/1078-0432.30705365https://figshare.com/articles/figure/Figure_6_from_Impact_of_Duration_of_Neoadjuvant_Aromatase_Inhibitors_on_Molecular_Expression_Profiles_in_Estrogen_Receptor_positive_Breast_Cancers/30705365CC BYinfo:eu-repo/semantics/openAccessoai:figshare.com:article/307053652025-11-25T12:05:23Z |
| spellingShingle | Figure 6 from Impact of Duration of Neoadjuvant Aromatase Inhibitors on Molecular Expression Profiles in Estrogen Receptor–positive Breast Cancers Milana A. Bergamino (15038015) Cancer Tumor Biology Cancer Detection and Diagnosis Therapeutic Research and Development Biomarkers Genetic biomarkers Breast Cancer Drug Resistance Novel mechanisms Endocrinology Translational Research |
| status_str | publishedVersion |
| title | Figure 6 from Impact of Duration of Neoadjuvant Aromatase Inhibitors on Molecular Expression Profiles in Estrogen Receptor–positive Breast Cancers |
| title_full | Figure 6 from Impact of Duration of Neoadjuvant Aromatase Inhibitors on Molecular Expression Profiles in Estrogen Receptor–positive Breast Cancers |
| title_fullStr | Figure 6 from Impact of Duration of Neoadjuvant Aromatase Inhibitors on Molecular Expression Profiles in Estrogen Receptor–positive Breast Cancers |
| title_full_unstemmed | Figure 6 from Impact of Duration of Neoadjuvant Aromatase Inhibitors on Molecular Expression Profiles in Estrogen Receptor–positive Breast Cancers |
| title_short | Figure 6 from Impact of Duration of Neoadjuvant Aromatase Inhibitors on Molecular Expression Profiles in Estrogen Receptor–positive Breast Cancers |
| title_sort | Figure 6 from Impact of Duration of Neoadjuvant Aromatase Inhibitors on Molecular Expression Profiles in Estrogen Receptor–positive Breast Cancers |
| topic | Cancer Tumor Biology Cancer Detection and Diagnosis Therapeutic Research and Development Biomarkers Genetic biomarkers Breast Cancer Drug Resistance Novel mechanisms Endocrinology Translational Research |