Table 1_Determinants of early lactation failure in mothers of moderately preterm neonates: a multilevel analysis of survey data.docx
Background<p>Early lactation failure among mothers of moderate preterm infants poses a persistent public health concern. This study identified key predictors and developed a risk stratification tool.</p>Methods<p>We conducted a prospective cohort study of 3,210 mother-infant dyads...
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2025
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| _version_ | 1849927637018869760 |
|---|---|
| author | Fei Hong (2659480) |
| author2 | Lei Song (30203) Xiaobin Chu (2231848) Yuanyuan Zhu (418127) Yan Wei (32168) Jiejie Wang (11830808) Rong Zou (2315830) Juhua Ji (22678625) |
| author2_role | author author author author author author author |
| author_facet | Fei Hong (2659480) Lei Song (30203) Xiaobin Chu (2231848) Yuanyuan Zhu (418127) Yan Wei (32168) Jiejie Wang (11830808) Rong Zou (2315830) Juhua Ji (22678625) |
| author_role | author |
| dc.creator.none.fl_str_mv | Fei Hong (2659480) Lei Song (30203) Xiaobin Chu (2231848) Yuanyuan Zhu (418127) Yan Wei (32168) Jiejie Wang (11830808) Rong Zou (2315830) Juhua Ji (22678625) |
| dc.date.none.fl_str_mv | 2025-11-25T05:10:47Z |
| dc.identifier.none.fl_str_mv | 10.3389/fnut.2025.1668778.s001 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/dataset/Table_1_Determinants_of_early_lactation_failure_in_mothers_of_moderately_preterm_neonates_a_multilevel_analysis_of_survey_data_docx/30703328 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Clinical and Sports Nutrition breastfeeding preterm infants lactation failure risk stratification self-efficacy maternal depression |
| dc.title.none.fl_str_mv | Table 1_Determinants of early lactation failure in mothers of moderately preterm neonates: a multilevel analysis of survey data.docx |
| dc.type.none.fl_str_mv | Dataset info:eu-repo/semantics/publishedVersion dataset |
| description | Background<p>Early lactation failure among mothers of moderate preterm infants poses a persistent public health concern. This study identified key predictors and developed a risk stratification tool.</p>Methods<p>We conducted a prospective cohort study of 3,210 mother-infant dyads (32.0–34.9 weeks gestation) at a tertiary hospital in China (February 2022–April 2025). Early lactation failure was defined as absence of direct breastfeeding with documented latch or provision of < 5 ml cumulative expressed breast milk within 72 h postpartum. Data included psychosocial assessments [breastfeeding self-efficacy scale-short form (BSES-SF), Edinburgh postnatal depression scale (EPDS), family support], obstetric factors, neonatal characteristics, and early care variables. Missing data was imputed using multiple chained equations (50 datasets). Multilevel logistic regression with ward-level random intercepts identified predictors, with bootstrap validation (1,000 resamples) assessing performance.</p>Results<p>Among 3,210 mother-infant dyads enrolled, 716 (22.3%) experienced early lactation failure within 72 h postpartum. Key predictors included higher BSES-SF scores [adjusted odds ratio (aOR) = 0.96 per point, 95% confidence interval (CI): 0.94–0.98], higher EPDS scores (aOR = 1.08, 95% CI: 1.04–1.12), cesarean delivery (aOR = 1.42, 95% CI: 1.15–1.75), neonatal respiratory support (aOR = 1.28, 95% CI: 1.05–1.56), and shorter kangaroo care duration (aOR = 0.92 per 10 min, 95% CI: 0.87–0.97). A five-factor risk tool stratified mothers into low-risk (13.0% failure rate), moderate-risk (20.5%), and high-risk (31.0%) groups, with strong discrimination (C-statistic = 0.704; calibration slope = 0.952; Hosmer-Lemeshow p = 0.267). Population-attributable risks were highest for cesarean delivery (20.4%), low self-efficacy (18.9%), and depression (18.2%), with numbers needed to treat (NNT) ranging from 11 to 18.</p>Conclusion<p>This study confirms the multifactorial basis of early lactation failure, highlighting maternal psychosocial factors as key predictors. The validated risk tool enables identification of high-risk dyads for targeted nutritional support interventions.</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_d7398cddc277fd1dac68afdcbb7bbed3 |
| identifier_str_mv | 10.3389/fnut.2025.1668778.s001 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/30703328 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Table 1_Determinants of early lactation failure in mothers of moderately preterm neonates: a multilevel analysis of survey data.docxFei Hong (2659480)Lei Song (30203)Xiaobin Chu (2231848)Yuanyuan Zhu (418127)Yan Wei (32168)Jiejie Wang (11830808)Rong Zou (2315830)Juhua Ji (22678625)Clinical and Sports Nutritionbreastfeedingpreterm infantslactation failurerisk stratificationself-efficacymaternal depressionBackground<p>Early lactation failure among mothers of moderate preterm infants poses a persistent public health concern. This study identified key predictors and developed a risk stratification tool.</p>Methods<p>We conducted a prospective cohort study of 3,210 mother-infant dyads (32.0–34.9 weeks gestation) at a tertiary hospital in China (February 2022–April 2025). Early lactation failure was defined as absence of direct breastfeeding with documented latch or provision of < 5 ml cumulative expressed breast milk within 72 h postpartum. Data included psychosocial assessments [breastfeeding self-efficacy scale-short form (BSES-SF), Edinburgh postnatal depression scale (EPDS), family support], obstetric factors, neonatal characteristics, and early care variables. Missing data was imputed using multiple chained equations (50 datasets). Multilevel logistic regression with ward-level random intercepts identified predictors, with bootstrap validation (1,000 resamples) assessing performance.</p>Results<p>Among 3,210 mother-infant dyads enrolled, 716 (22.3%) experienced early lactation failure within 72 h postpartum. Key predictors included higher BSES-SF scores [adjusted odds ratio (aOR) = 0.96 per point, 95% confidence interval (CI): 0.94–0.98], higher EPDS scores (aOR = 1.08, 95% CI: 1.04–1.12), cesarean delivery (aOR = 1.42, 95% CI: 1.15–1.75), neonatal respiratory support (aOR = 1.28, 95% CI: 1.05–1.56), and shorter kangaroo care duration (aOR = 0.92 per 10 min, 95% CI: 0.87–0.97). A five-factor risk tool stratified mothers into low-risk (13.0% failure rate), moderate-risk (20.5%), and high-risk (31.0%) groups, with strong discrimination (C-statistic = 0.704; calibration slope = 0.952; Hosmer-Lemeshow p = 0.267). Population-attributable risks were highest for cesarean delivery (20.4%), low self-efficacy (18.9%), and depression (18.2%), with numbers needed to treat (NNT) ranging from 11 to 18.</p>Conclusion<p>This study confirms the multifactorial basis of early lactation failure, highlighting maternal psychosocial factors as key predictors. The validated risk tool enables identification of high-risk dyads for targeted nutritional support interventions.</p>2025-11-25T05:10:47ZDatasetinfo:eu-repo/semantics/publishedVersiondataset10.3389/fnut.2025.1668778.s001https://figshare.com/articles/dataset/Table_1_Determinants_of_early_lactation_failure_in_mothers_of_moderately_preterm_neonates_a_multilevel_analysis_of_survey_data_docx/30703328CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/307033282025-11-25T05:10:47Z |
| spellingShingle | Table 1_Determinants of early lactation failure in mothers of moderately preterm neonates: a multilevel analysis of survey data.docx Fei Hong (2659480) Clinical and Sports Nutrition breastfeeding preterm infants lactation failure risk stratification self-efficacy maternal depression |
| status_str | publishedVersion |
| title | Table 1_Determinants of early lactation failure in mothers of moderately preterm neonates: a multilevel analysis of survey data.docx |
| title_full | Table 1_Determinants of early lactation failure in mothers of moderately preterm neonates: a multilevel analysis of survey data.docx |
| title_fullStr | Table 1_Determinants of early lactation failure in mothers of moderately preterm neonates: a multilevel analysis of survey data.docx |
| title_full_unstemmed | Table 1_Determinants of early lactation failure in mothers of moderately preterm neonates: a multilevel analysis of survey data.docx |
| title_short | Table 1_Determinants of early lactation failure in mothers of moderately preterm neonates: a multilevel analysis of survey data.docx |
| title_sort | Table 1_Determinants of early lactation failure in mothers of moderately preterm neonates: a multilevel analysis of survey data.docx |
| topic | Clinical and Sports Nutrition breastfeeding preterm infants lactation failure risk stratification self-efficacy maternal depression |