Data Sheet 12_Enterohemorrhagic Escherichia coli O157 outer membrane vesicles administered by oral gavage cause renal tubular injury and acute kidney failure in mice.pdf

Data Sheet 12_Enterohemorrhagic Escherichia coli O157 outer membrane vesicles administered by oral gavage cause renal tubular injury and acute kidney failure in mice.pdf

Background<p>Outer membrane vesicles (OMVs) secreted by enterohemorrhagic Escherichia coli (EHEC) O157 contain Shiga toxin 2 (Stx2), the major virulence factor involved in the pathogenesis of EHEC-associated hemolytic uremic syndrome (EHEC-HUS). However, it remains unclear whether EHEC OMVs pr...

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Hlavní autor: Jaromír Háček (22671836) (author)
Další autoři: Alena Vlková (22671839) (author), Daniel Krsek (11595178) (author), Lukáš Kolařík (22671842) (author), Alžběta Spálenková (22671845) (author), Tomáš Sychra (22671848) (author), Tereza Tesařová (22671851) (author), Emin Gayibov (22671854) (author), Radka Václavíková (606637) (author), Jakub Zieg (11416838) (author), Martina Bielaszewska (79970) (author)
Vydáno: 2025
Témata:
Clinical Microbiology
enterohemorrhagic Escherichia coli (EHEC)
Shiga toxin
outer membrane vesicles
mouse model
oral gavage
hemolytic uremic syndrome
renal tubular damage
acute kidney failure
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