Supplementary file 1_Harnessing marine algal polysaccharides for combination cancer therapy: pharmacological mechanisms and clinical perspectives.docx
<p>Algal polysaccharides (APs) have attracted increasing interest in recent years as adjunctive agents in cancer therapy due to their abundance, low toxicity, and diverse bioactivity. This review explores the pharmacological effects and mechanisms of APs in combination with chemotherapy, radio...
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2025
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| _version_ | 1849927636038451200 |
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| author | Jing Zhong (230059) |
| author2 | Sookja Kim Chung (14057157) Xiaoling Han (14707343) Riming Huang (544983) Baojun Xu (3714874) Io Nam Wong (20299705) |
| author2_role | author author author author author |
| author_facet | Jing Zhong (230059) Sookja Kim Chung (14057157) Xiaoling Han (14707343) Riming Huang (544983) Baojun Xu (3714874) Io Nam Wong (20299705) |
| author_role | author |
| dc.creator.none.fl_str_mv | Jing Zhong (230059) Sookja Kim Chung (14057157) Xiaoling Han (14707343) Riming Huang (544983) Baojun Xu (3714874) Io Nam Wong (20299705) |
| dc.date.none.fl_str_mv | 2025-11-25T06:24:08Z |
| dc.identifier.none.fl_str_mv | 10.3389/fphar.2025.1682025.s001 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/dataset/Supplementary_file_1_Harnessing_marine_algal_polysaccharides_for_combination_cancer_therapy_pharmacological_mechanisms_and_clinical_perspectives_docx/30703961 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Pharmacology algal polysaccharides combination cancer therapy anti-cancer pharmacological effects therapeutic safety enhancement |
| dc.title.none.fl_str_mv | Supplementary file 1_Harnessing marine algal polysaccharides for combination cancer therapy: pharmacological mechanisms and clinical perspectives.docx |
| dc.type.none.fl_str_mv | Dataset info:eu-repo/semantics/publishedVersion dataset |
| description | <p>Algal polysaccharides (APs) have attracted increasing interest in recent years as adjunctive agents in cancer therapy due to their abundance, low toxicity, and diverse bioactivity. This review explores the pharmacological effects and mechanisms of APs in combination with chemotherapy, radiotherapy, and immunotherapy, as well as their potential as a nano medicine delivery system. It highlights a wide range of biological activities exhibited by APs in combination therapy, including enhanced tumor cell killing, modulation of the tumor immune microenvironment, and protection of healthy tissues from treatment-related toxicity. Furthermore, the review summarizes the advancements in the pharmacodynamics, pharmacokinetics, and safety profiles of APs, emphasizing the need for standardized raw materials, combined strengths analysis, and clinical validation as key future directions.</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_d9544ecb8067d74168d7af42453be1fa |
| identifier_str_mv | 10.3389/fphar.2025.1682025.s001 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/30703961 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Supplementary file 1_Harnessing marine algal polysaccharides for combination cancer therapy: pharmacological mechanisms and clinical perspectives.docxJing Zhong (230059)Sookja Kim Chung (14057157)Xiaoling Han (14707343)Riming Huang (544983)Baojun Xu (3714874)Io Nam Wong (20299705)Pharmacologyalgal polysaccharidescombination cancer therapyanti-cancerpharmacological effectstherapeutic safety enhancement<p>Algal polysaccharides (APs) have attracted increasing interest in recent years as adjunctive agents in cancer therapy due to their abundance, low toxicity, and diverse bioactivity. This review explores the pharmacological effects and mechanisms of APs in combination with chemotherapy, radiotherapy, and immunotherapy, as well as their potential as a nano medicine delivery system. It highlights a wide range of biological activities exhibited by APs in combination therapy, including enhanced tumor cell killing, modulation of the tumor immune microenvironment, and protection of healthy tissues from treatment-related toxicity. Furthermore, the review summarizes the advancements in the pharmacodynamics, pharmacokinetics, and safety profiles of APs, emphasizing the need for standardized raw materials, combined strengths analysis, and clinical validation as key future directions.</p>2025-11-25T06:24:08ZDatasetinfo:eu-repo/semantics/publishedVersiondataset10.3389/fphar.2025.1682025.s001https://figshare.com/articles/dataset/Supplementary_file_1_Harnessing_marine_algal_polysaccharides_for_combination_cancer_therapy_pharmacological_mechanisms_and_clinical_perspectives_docx/30703961CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/307039612025-11-25T06:24:08Z |
| spellingShingle | Supplementary file 1_Harnessing marine algal polysaccharides for combination cancer therapy: pharmacological mechanisms and clinical perspectives.docx Jing Zhong (230059) Pharmacology algal polysaccharides combination cancer therapy anti-cancer pharmacological effects therapeutic safety enhancement |
| status_str | publishedVersion |
| title | Supplementary file 1_Harnessing marine algal polysaccharides for combination cancer therapy: pharmacological mechanisms and clinical perspectives.docx |
| title_full | Supplementary file 1_Harnessing marine algal polysaccharides for combination cancer therapy: pharmacological mechanisms and clinical perspectives.docx |
| title_fullStr | Supplementary file 1_Harnessing marine algal polysaccharides for combination cancer therapy: pharmacological mechanisms and clinical perspectives.docx |
| title_full_unstemmed | Supplementary file 1_Harnessing marine algal polysaccharides for combination cancer therapy: pharmacological mechanisms and clinical perspectives.docx |
| title_short | Supplementary file 1_Harnessing marine algal polysaccharides for combination cancer therapy: pharmacological mechanisms and clinical perspectives.docx |
| title_sort | Supplementary file 1_Harnessing marine algal polysaccharides for combination cancer therapy: pharmacological mechanisms and clinical perspectives.docx |
| topic | Pharmacology algal polysaccharides combination cancer therapy anti-cancer pharmacological effects therapeutic safety enhancement |