Expression of TF and HK-II in stable and vulnerable coronary atherosclerotic plaques.

<p><b>(A)</b> Representative histological and immunohistochemical images of a fibrous cap atheroma (stable lesions). In the high-magnification images (square), the stable plaque shows a mild infiltrate of CD68-immunopositive cells around the necrotic core and modest expression of T...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Kazunari Maekawa (14642343) (author)
مؤلفون آخرون: Eriko Nakamura (14642340) (author), Yoichi Saito (2435818) (author), Yunosuke Matsuura (513639) (author), Toshihiro Gi (20827051) (author), Kensaku Nishihira (4745643) (author), Nobuyuki Oguri (20827054) (author), Sayaka Moriguchi-Goto (513641) (author), Yuichiro Sato (306682) (author), Kinta Hatakeyama (621292) (author), Yoshisato Shibata (4231030) (author), Yoshihiro Komohara (414247) (author), Koichi Kaikita (3342230) (author), Yujiro Asada (513646) (author), Atsushi Yamashita (283413) (author)
منشور في: 2025
الموضوعات:
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الوصف
الملخص:<p><b>(A)</b> Representative histological and immunohistochemical images of a fibrous cap atheroma (stable lesions). In the high-magnification images (square), the stable plaque shows a mild infiltrate of CD68-immunopositive cells around the necrotic core and modest expression of TF and HK-II. <b>(B)</b> Representative histological and immunohistochemical images of a thin-cap fibroatheroma (vulnerable lesions). In the high-magnification images (square), the vulnerable plaque shows the presence of CD68-immunopositive cells in the fibrous cap and necrotic core. TF- and HK-II-immunopositive cells are predominantly localized in macrophage-rich areas. <b>(C)</b> Representative immunohistochemical high-magnification images of a thin-cap fibroatheroma (vulnerable lesions). CD68-immunopositive cells are immunopositive for TF and HK-II (arrow) but not SMA.</p>