Hepatic cholesterol biosynthesis through the mevalonate pathway as one of the anchor models.

<p>The various components of the biosynthetic mevalonate pathway system are color-coded by type, as indicated. Metabolic reactions, transport steps, and the production of mRNAs and proteins are shown as solid lines, while regulatory signals, representing feedback inhibition (red) and modulatio...

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Bibliographic Details
Main Author:	Carla M. Kumbale (15309073) (author)
Other Authors:	Qiang Zhang (45005) (author), Eberhard O. Voit (7377512) (author)
Published:	2025
Subjects:	Medicine Genetics Neuroscience Biotechnology Cancer Science Policy Biological Sciences not elsewhere classified Information Systems not elsewhere classified sex hormone steroidogenesis represent component sub new approach methodology main physiological processes lower biological levels body &# 8217 grained model capturing xlink "> dioxins modeling paradigm enables cholesterol biosynthesis via third anchor model overall health impact multiple health effects modeling paradigm human health template model well documented systemic effects skin rashes reproductive toxicity powerful tool personalized medicine novel adaptation mevalonate pathway menstrual cycle mediated effects liver dysfunction level coarse holistic evaluation greater detail future may dioxins remains developed previously comprehensive understanding cholesterol transport anchor models
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Hepatic cholesterol biosynthesis through the mevalonate pathway as one of the anchor models.

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