Supplementary file 2_Lycii radicis cortex alleviates fibrosis in hiPSC-derived multilineage hepatic organoids via the cAMP-PKA pathway.docx

Background<p>Liver fibrosis, driven by excessive extracellular matrix (ECM) deposition and activation of hepatic stellate cells (HSCs), still lacks effective therapies, partly due to the absence of human-relevant models. Lycii Radicis Cortex (LRC), a traditional Chinese medicine, exhibits repo...

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Autor principal:	Junming Xu (1716112) (author)
Altres autors:	Xiaopu Sang (8502954) (author), Yongfei He (21372968) (author), Jie Ke (2005411) (author), Jiasen Xu (729951) (author), Tanbin Liu (4849807) (author), Jicai Wang (21372977) (author), Hang Zhai (1540051) (author), Xiaoni Chen (8502957) (author), Xianjie Shi (3567419) (author), Fenfang Wu (3157299) (author)
Publicat:	2025
Matèries:	Pharmacology natural products IPSCs (induced pluripotent stem cells) organoid liver fibrosis lycii radicis cortex cAMP–PKA–CREB pathway
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Supplementary file 2_Lycii radicis cortex alleviates fibrosis in hiPSC-derived multilineage hepatic organoids via the cAMP-PKA pathway.docx

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