KEGG analysis of downregulated DEPs.

KEGG analysis of downregulated DEPs.

<div><p>Objective</p><p>Radiation-induced brain injury (RIBI) is a significant complication following radiotherapy for brain tumors, leading to neurocognitive deficits and other neurological impairments. This study aims to identify potential biomarkers and therapeutic targets...

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Αποθηκεύτηκε σε:

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριος συγγραφέας:	Jing Liu (38537) (author)
Άλλοι συγγραφείς:	Junshuang Wang (22683435) (author), Shuang Lv (660117) (author), Hengjiao Wang (21539904) (author), Defu Yang (735577) (author), Ying Zhang (40767) (author), Ying Li (38224) (author), Huiling Qu (6104225) (author), Ying Xu (9172) (author), Ying Yan (47692) (author)
Έκδοση:	2025
Θέματα:	Biophysics Biochemistry Medicine Cell Biology Genetics Molecular Biology Neuroscience Pharmacology Evolutionary Biology Cancer Mental Health Infectious Diseases Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified tandem mass tagging resolution mass spectrometry 30 gy ). induced brain injury ribi &# 8217 ppi network analysis key hub protein kegg analysis highlighted identifying key proteins xlink "> radiation identify potential biomarkers xlink "> potential biomarkers potential role brain tumors brain tissues brain tissue brain irradiation tight junctions therapeutic targets targeted therapies study aims ribi pathophysiology rat model protein interaction ppar signaling pathways related pathways involved pathway analyses neurological impairments neurocognitive deficits molecular pathology molecular mechanisms mitigate radiation metabolic processes mainly involved lipid transport kyoto encyclopedia irradiated rats increased expression gene ontology findings suggest could serve clinical intervention cell adhesion biological processes associated pathways
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Παρόμοια τεκμήρια

KEGG enrichment analysis of DEPs.
ανά: Jing Liu (38537)
Έκδοση: (2025)

KEGG analysis of upregulated DEPs.
ανά: Jing Liu (38537)
Έκδοση: (2025)

GO analysis of downregulated DEPs.
ανά: Jing Liu (38537)
Έκδοση: (2025)

PPI network analysis of DEPs.
ανά: Jing Liu (38537)
Έκδοση: (2025)

GO enrichment analysis of DEPs.
ανά: Jing Liu (38537)
Έκδοση: (2025)

GO analysis of upregulated DEPs.
ανά: Jing Liu (38537)
Έκδοση: (2025)

DEPs based on subcellular localization.
ανά: Jing Liu (38537)
Έκδοση: (2025)

DEPs based on structural domains.
ανά: Jing Liu (38537)
Έκδοση: (2025)

Classification of DEPs based on structural domains and subcellular localization.
ανά: Jing Liu (38537)
Έκδοση: (2025)

Volcano plot and heatmap of DEPs between RIBI and control tissues.
ανά: Jing Liu (38537)
Έκδοση: (2025)

Immunohistochemical staining for PHLDA3, APOE, and CPE in irradiated brain tissues.
ανά: Jing Liu (38537)
Έκδοση: (2025)

Principal component analysis and repeatability analysis.
ανά: Jing Liu (38537)
Έκδοση: (2025)

Representative HE staining images of brain tissues.
ανά: Jing Liu (38537)
Έκδοση: (2025)

Differentially expressed proteins.
ανά: Jing Liu (38537)
Έκδοση: (2025)

Fluvastatin inhibits the migration of melanoma A375 cells in a wound healing assay.
ανά: Jingxin Zeng (18773484)
Έκδοση: (2025)

Discovery of therapeutic compounds targeting brain metastasis-associated tumor cells (MBMATCs) in high MBM-Index melanoma.
ανά: Jingxin Zeng (18773484)
Έκδοση: (2025)

The MBM-Index as an independent predictor of overall survival (OS) in melanoma.
ανά: Jingxin Zeng (18773484)
Έκδοση: (2025)

Identification of melanoma brain metastasis-associated tumor cell subpopulations (MBMATCs).
ανά: Jingxin Zeng (18773484)
Έκδοση: (2025)

Tumor cell-specific transcriptomic features across PTs, ECMs and MBMs.
ανά: Jingxin Zeng (18773484)
Έκδοση: (2025)

Immune landscape and CD8<sup>+</sup> T cell transition states in PTs, ECMs and MBMs.
ανά: Jingxin Zeng (18773484)
Έκδοση: (2025)

Single cell RNA-seq and snRNA-seq profiling of the PTs (primary melanoma), ECMs (extracranial melanoma metastases) and MBMs (melanoma brain metastases) environments.
ανά: Jingxin Zeng (18773484)
Έκδοση: (2025)

Samples & cell type composition in melanoma tumor cells.
ανά: Jingxin Zeng (18773484)
Έκδοση: (2025)

Marker genes in melanoma tumor cells across PT, ECM and MBM by sc/snRNA-seq.
ανά: Jingxin Zeng (18773484)
Έκδοση: (2025)

AXL and MITF signature genes.
ανά: Jingxin Zeng (18773484)
Έκδοση: (2025)

Samples & cell type composition in sc/snRNA-seq.
ανά: Jingxin Zeng (18773484)
Έκδοση: (2025)

Identification of therapeutic drugs with high drug sensitivity for brain metastasis-associated tumor cells (MBMATCs) and high-brain metastasis (MBM) index patients.
ανά: Jingxin Zeng (18773484)
Έκδοση: (2025)

The enriched pathway by all transcripts differentially expressed between MBMATCs and other tumor cells, and between MBM-High and MBM-Low groups.
ανά: Jingxin Zeng (18773484)
Έκδοση: (2025)

The MBM-Index showed no significant correlation with clinicopathological features.
ανά: Jingxin Zeng (18773484)
Έκδοση: (2025)

Interaction between MBMATCs and the immune microenvironment.
ανά: Jingxin Zeng (18773484)
Έκδοση: (2025)

Pseudotime trajectory analysis of melanoma clusters Mela4 and Mela5.
ανά: Jingxin Zeng (18773484)
Έκδοση: (2025)

Immune cells profiling in PTs, ECMs and MBMs.
ανά: Jingxin Zeng (18773484)
Έκδοση: (2025)

scRNA-seq and snRNA-seq profiling of 26 melanoma samples.
ανά: Jingxin Zeng (18773484)
Έκδοση: (2025)

Supplementary Figure S1 from Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX
ανά: Rumani Singh (17141575)
Έκδοση: (2025)

Supplementary Figure S2 from Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX
ανά: Rumani Singh (17141575)
Έκδοση: (2025)

Supplementary Figure S3 from Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX
ανά: Rumani Singh (17141575)
Έκδοση: (2025)

Supplementary Figure S4 from Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX
ανά: Rumani Singh (17141575)
Έκδοση: (2025)

Supplementary Figure S5 from Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX
ανά: Rumani Singh (17141575)
Έκδοση: (2025)

Supplementary Figure S6 from Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX
ανά: Rumani Singh (17141575)
Έκδοση: (2025)

Table 1_Cerebrospinal fluid proteomic profiling reveals potential biomarkers and altered pathways in myotonic dystrophy type 1.docx
ανά: Marwa Zafarullah (12527002)
Έκδοση: (2025)

Statistical comparison (<i>p</i>-values) of Lempel-Ziv complexity (LZC) and Permutation Entropy (PE), for low frequency components of the signal across sleep states within each condition.
ανά: Magaly Catanzariti (20865500)
Έκδοση: (2025)

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