Image 5_Optimised dissociation and multimodal profiling of prostate cancer stroma reveal fibromuscular cell heterogeneity with clinical correlates.tiff

Image 5_Optimised dissociation and multimodal profiling of prostate cancer stroma reveal fibromuscular cell heterogeneity with clinical correlates.tiff

Background<p>Dynamic remodelling of the tumour microenvironment (TME) plays a central role in prostate cancer (PCa) progression, immune evasion and therapy resistance. However, the co-existence of both tumour-promoting and tumour-restraining stromal elements necessitates extensive characterisa...

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Detalhes bibliográficos
Autor principal: Elisabeth Damisch (22679276) (author)
Outros Autores: Elena Brunner (11153976) (author), Lukas Nommensen (22679279) (author), Lucy Neumann (22679282) (author), Georgios Fotakis (9598167) (author), Zlatko Trajanoski (15774) (author), Sieghart Sopper (823900) (author), Georg Schäfer (279214) (author), Martin Puhr (697731) (author), Isabel Heidegger (689987) (author), Marianna Kruithof-de Julio (9014339) (author), Natalie Sampson (6414767) (author)
Publicado em: 2025
Assuntos:
Cell Biology
cancer-associated fibroblast
prostate cancer
smooth muscle cell
tissue dissociation
single cell RNA sequencing
tumour microenvironment
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