Overview of MitoTracer algorithm.

<p>(A) The whole analysis process of identifying informative MT mutations. MERCI-mtSNP calls MT mutations from single cell RNA or DNA sequencing data. The VAF matrix is generated for MitoTracer. (B) Informative MT mutation selection. MitoTracer firstly removes mutations caused by sequencing er...

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Bibliographic Details
Main Author:	Xuexin Yu (733842) (author)
Other Authors:	Jing Hu (41899) (author), Yuhao Tan (15227659) (author), Mingyao Pan (21587178) (author), Hongyi Zhang (431841) (author), Bo Li (112195) (author)
Published:	2025
Subjects:	Genetics Molecular Biology Evolutionary Biology Cancer Infectious Diseases Plant Biology Biological Sciences not elsewhere classified Information Systems not elsewhere classified xlink "> mitochondrial natural genetic markers mutated cancer cells inferred evolutionary lineage existing methods measured informative mitochondrial mutations benchmarked mitotracer using based lineage tracing informative mt mutations mutations serve work provided valuable tool superior performance mt mutation mitotracer facilitates inhibitor resistance high sensitivity genes related fundamental challenge
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Overview of MitoTracer algorithm.

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