Figure S5 from Auranofin Synergizes with Cisplatin in Reducing Tumor Burden of NOTCH-Dependent Ovarian Cancer

Figure S5 from Auranofin Synergizes with Cisplatin in Reducing Tumor Burden of NOTCH-Dependent Ovarian Cancer

<p>Supplementary Figure S5 presents responses of PDX-derived cancer organoids to cisplatin, auranofin, or their combination versus mock treatment: panels A–B show PDXO2 and panels C–D show PDXO1 (mean ± SEM, n > 5). Panel E displays anti-RBPJ ChIP-qPCR in PDXO1 organoids treated with DMSO o...

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Bibliographic Details
Main Author: Robert J. Lake (22408833) (author)
Other Authors: Parisa Nikeghbal (22408836) (author), Irina V. Lagutina (15133518) (author), Kimberly K. Leslie (22408839) (author), Mara P. Steinkamp (15136266) (author), Hua-Ying Fan (22408842) (author)
Published: 2025
Subjects:
Cancer
Therapeutic Research and Development
Methods and Technology
Combination Chemotherapy
Drug Targets
Oncoprotein & tumor suppressor drug targets
Ovarian Cancer
Preclinical Models
Organoids
Reversal Of Drug Resistance
Xenograft Models
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