For the data sets with 1,500 case-trios, panels (a) and (b) showed the true and false positive rates of analyzing regions using both common and rare variants; panels (c) and (d) showed the true and false positive rates of regions with rare variants only.

<p>For the data sets with 1,500 case-trios, panels (a) and (b) showed the true and false positive rates of analyzing regions using both common and rare variants; panels (c) and (d) showed the true and false positive rates of regions with rare variants only.</p>

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Bibliographic Details
Main Author:	Duo Yu (4243240) (author)
Other Authors:	Matthew Koslovsky (20384073) (author), Margaret C. Steiner (13844003) (author), Kusha Mohammadi (20384076) (author), Chenguang Zhang (457185) (author), Michael D. Swartz (10139250) (author)
Published:	2024
Subjects:	Biochemistry Genetics Molecular Biology Evolutionary Biology Sociology Plant Biology Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified transmission disequilibrium test false positive rates burden association tests use pedigree data simultaneously detect common 30 %, respectively trio_rvemvs performed competitively individual variants level rare variants may individual rare variants trio_rvemvs outperformed pedgene common variants rare variants real data 20 %, region level level kernel applying trio_rvemvs xlink "> variant extensions trio rvemvs paper proposes outperformed rv orofacial clefts functionally related complex diseases commonly reported bayesian framework average true available samples 74 %. 500 trios 350 trios 350 families 22 associated 1500 families
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For the data sets with 1,500 case-trios, panels (a) and (b) showed the true and false positive rates of analyzing regions using both common and rare variants; panels (c) and (d) showed the true and false positive rates of regions with rare variants only.

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