The novel thioredoxin reductase inhibitor butaselen suppresses lung cancer by inducing oxidative stress

The novel thioredoxin reductase inhibitor butaselen suppresses lung cancer by inducing oxidative stress

<p>Lung cancer is one of the leading causes of cancer-related deaths worldwide with limited treatment options available. The anti-tumor effects of the TrxR inhibitor Butaselen (BS/BS1801) on lung cancer and its underlying mechanisms remain unknown.</p> <p>This study utilized lung c...

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Bibliographic Details
Main Author: Yifan Chen (446592) (author)
Other Authors: Guangliang Qiang (296666) (author), Liang Jin (316008) (author), Yan Sun (22436) (author), Guozhou Zhang (22688355) (author), Fengling Hu (3595472) (author), Jinhui Feng (269301) (author), Feng Wei (426184) (author), Shengxin Zeng (22688358) (author), Lixiang Xue (23235) (author), Huihui Zeng (6700337) (author), Shaohua Ma (8746758) (author)
Published: 2025
Subjects:
Biochemistry
Medicine
Microbiology
Cell Biology
Molecular Biology
Pharmacology
Developmental Biology
Cancer
Infectious Diseases
Virology
Biological Sciences not elsewhere classified
Lung cancer
oxidative stress
thioredoxin reductase
butaselen
apoptosis
high-mobility group box-containing protein 1 (HBP1)
ubiquitination
DNA methylation
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