Smart Cutter: An Efficient Strategy for Increasing the Coverage of Chemical Cross-Linking Analysis

Smart Cutter: An Efficient Strategy for Increasing the Coverage of Chemical Cross-Linking Analysis

Chemical cross-linking combined with mass spectrometry (CXMS) has emerged as a powerful tool to study protein structure, conformation, and protein–protein interactions (PPIs). Until now, most cross-linked peptides were generated by using commercial cross-linkers, such as DSS, BS<sup>3</sup&...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Lili Zhao (442802) (author)
مؤلفون آخرون: Qun Zhao (603175) (author), Yichu Shan (271771) (author), Fei Fang (64051) (author), Weijie Zhang (145595) (author), Baofeng Zhao (479410) (author), Xiao Li (107004) (author), Zhen Liang (659089) (author), Lihua Zhang (22614) (author), Yukui Zhang (1413592) (author)
منشور في: 2019
الموضوعات:
Biophysics
Biochemistry
Genetics
Biotechnology
Immunology
Developmental Biology
Cancer
Infectious Diseases
Biological Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
BS
sequential digestion strategy
60 kDa chaperonin protein
CXMS
cross-linked peptides
MS
trypsin
protein structure
DSS cross-linked E
Chemical Cross-Linking Analysis Chemical cross-linking
site
DSSO
PPI
study protein structure
protein interaction network
protein structure information
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