Dispersin B solution +  1% benzoyl peroxide kills <i>C. acnes</i> biofilms as efficiently as 2.5% benzoyl peroxide alone.

<p>24-h-old aerobic <i>C. acnes</i>/<i>S. epidermidis</i> dual-species biofilms were rinsed and treated for 15 min with phosphate buffered saline (PBS), 80 µg/ml dispersin B solution (Dsp), or 1% or 2.5% benzoyl peroxide (BP1 and BP2.5, respectively), then rinsed and su...

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Bibliographic Details
Main Author: Jeffrey B. Kaplan (582873) (author)
Other Authors: Anna Muzaleva (20947781) (author), Miloslav Sailer (1853182) (author), Robert B. Huizinga (20888414) (author), Khalaf Kridin (7523390) (author)
Published: 2025
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Summary:<p>24-h-old aerobic <i>C. acnes</i>/<i>S. epidermidis</i> dual-species biofilms were rinsed and treated for 15 min with phosphate buffered saline (PBS), 80 µg/ml dispersin B solution (Dsp), or 1% or 2.5% benzoyl peroxide (BP1 and BP2.5, respectively), then rinsed and subjected to a second 15-min treatment with PBS or BP1 in the combinations indicated at the top. Graphs show CFU/tube values for <i>S. epidermidis</i> (left panel) and C<i>. acnes</i> (right panel) from triplicate tubes for each treatment. Each dot represents one tube. Horizontal bars indicate means.</p>