Model of multiple myeloma treatment with Dara (control, <i>u</i>), including an immune response (purple arrows) and drug resistance mechanisms via loss of CD38 expression.

<p>The cell populations are healthy marrow cells (<i>A</i>), CD38+ cancer and CD38− cancer , and all arrows represent movement of cells between populations or states. Three drug actions are included (green arrows): cell mortality and loss of CD38 expression in the CD38+ cancer cell...

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主要作者: James G. Lefevre (11303976) (author)
其他作者: Brodie A. J. Lawson (8771843) (author), Pamela M. Burrage (16938568) (author), Diane M. Donovan (22033185) (author), Kevin Burrage (21168) (author)
出版: 2025
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