Large state-wide variation (10.2-fold) in number of clozapine prescriptions per thousand Medicare Part D enrollees in 2016 <sup>a</sup> indicates ≥1.50 SD (19.2) from the mean (34.8), which is denoted by the dotted line. <sup>b</sup> indicates ≥1.96 SD from the mean.
<p>Large state-wide variation (10.2-fold) in number of clozapine prescriptions per thousand Medicare Part D enrollees in 2016 <sup>a</sup> indicates ≥1.50 SD (19.2) from the mean (34.8), which is denoted by the dotted line. <sup>b</sup> indicates ≥1.96 SD from the mean....
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2025
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Ավելացրեք ցուցիչ
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| _version_ | 1851483667327614976 |
|---|---|
| author | Luke R. Cavanah (19022435) |
| author2 | Maria Y. Tian (22075705) Jessica L. Goldhirsh (16229023) Leighton Y. Huey (19022438) Brian J. Piper (9870935) |
| author2_role | author author author author |
| author_facet | Luke R. Cavanah (19022435) Maria Y. Tian (22075705) Jessica L. Goldhirsh (16229023) Leighton Y. Huey (19022438) Brian J. Piper (9870935) |
| author_role | author |
| dc.creator.none.fl_str_mv | Luke R. Cavanah (19022435) Maria Y. Tian (22075705) Jessica L. Goldhirsh (16229023) Leighton Y. Huey (19022438) Brian J. Piper (9870935) |
| dc.date.none.fl_str_mv | 2025-08-18T17:43:54Z |
| dc.identifier.none.fl_str_mv | 10.1371/journal.pone.0328495.s002 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/figure/Large_state-wide_variation_10_2-fold_in_number_of_clozapine_prescriptions_per_thousand_Medicare_Part_D_enrollees_in_2016_sup_a_sup_indicates_1_50_SD_19_2_from_the_mean_34_8_which_is_denoted_by_the_dotted_line_sup_b_sup_indicates_1_96_SD_fro/29934160 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Genetics Immunology Cancer Mental Health Environmental Sciences not elsewhere classified underutilization &# 8212 substantial economic burden spending (&# 8722 reduced suicide ideation medication &# 8217 cause mortality benefits associated management requirements adverse effect profile xlink "> schizophrenia pronounced geographic heterogeneity alleviating schizophrenia symptoms historically underutilized clozapine characterize clozapine utilization us medicaid recipients population (&# 8722 poor treatment adherence patterns previously identified 2015 &# 8722 corrected clozapine use clozapine use adjusted pronounced state variation us medicare patients pronounced state medicare patients clozapine use resistant schizophrenia level variation substance use training reform steady decrease spectrum disorders south dakota prescribed significantly practical solutions inadequate training education interventions demonstrated effectiveness 9 %) |
| dc.title.none.fl_str_mv | Large state-wide variation (10.2-fold) in number of clozapine prescriptions per thousand Medicare Part D enrollees in 2016 <sup>a</sup> indicates ≥1.50 SD (19.2) from the mean (34.8), which is denoted by the dotted line. <sup>b</sup> indicates ≥1.96 SD from the mean. |
| dc.type.none.fl_str_mv | Image Figure info:eu-repo/semantics/publishedVersion image |
| description | <p>Large state-wide variation (10.2-fold) in number of clozapine prescriptions per thousand Medicare Part D enrollees in 2016 <sup>a</sup> indicates ≥1.50 SD (19.2) from the mean (34.8), which is denoted by the dotted line. <sup>b</sup> indicates ≥1.96 SD from the mean.</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_eb2ac54d6f6273452c5bb9fb1bca2f50 |
| identifier_str_mv | 10.1371/journal.pone.0328495.s002 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/29934160 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Large state-wide variation (10.2-fold) in number of clozapine prescriptions per thousand Medicare Part D enrollees in 2016 <sup>a</sup> indicates ≥1.50 SD (19.2) from the mean (34.8), which is denoted by the dotted line. <sup>b</sup> indicates ≥1.96 SD from the mean.Luke R. Cavanah (19022435)Maria Y. Tian (22075705)Jessica L. Goldhirsh (16229023)Leighton Y. Huey (19022438)Brian J. Piper (9870935)GeneticsImmunologyCancerMental HealthEnvironmental Sciences not elsewhere classifiedunderutilization &# 8212substantial economic burdenspending (&# 8722reduced suicide ideationmedication &# 8217cause mortality benefitsassociated management requirementsadverse effect profilexlink "> schizophreniapronounced geographic heterogeneityalleviating schizophrenia symptomshistorically underutilized clozapinecharacterize clozapine utilizationus medicaid recipientspopulation (&# 8722poor treatment adherencepatterns previously identified2015 &# 8722corrected clozapine useclozapine use adjustedpronounced state variationus medicare patientspronounced statemedicare patientsclozapine useresistant schizophrenialevel variationsubstance usetraining reformsteady decreasespectrum disorderssouth dakotaprescribed significantlypractical solutionsinadequate trainingeducation interventionsdemonstrated effectiveness9 %)<p>Large state-wide variation (10.2-fold) in number of clozapine prescriptions per thousand Medicare Part D enrollees in 2016 <sup>a</sup> indicates ≥1.50 SD (19.2) from the mean (34.8), which is denoted by the dotted line. <sup>b</sup> indicates ≥1.96 SD from the mean.</p>2025-08-18T17:43:54ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1371/journal.pone.0328495.s002https://figshare.com/articles/figure/Large_state-wide_variation_10_2-fold_in_number_of_clozapine_prescriptions_per_thousand_Medicare_Part_D_enrollees_in_2016_sup_a_sup_indicates_1_50_SD_19_2_from_the_mean_34_8_which_is_denoted_by_the_dotted_line_sup_b_sup_indicates_1_96_SD_fro/29934160CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/299341602025-08-18T17:43:54Z |
| spellingShingle | Large state-wide variation (10.2-fold) in number of clozapine prescriptions per thousand Medicare Part D enrollees in 2016 <sup>a</sup> indicates ≥1.50 SD (19.2) from the mean (34.8), which is denoted by the dotted line. <sup>b</sup> indicates ≥1.96 SD from the mean. Luke R. Cavanah (19022435) Genetics Immunology Cancer Mental Health Environmental Sciences not elsewhere classified underutilization &# 8212 substantial economic burden spending (&# 8722 reduced suicide ideation medication &# 8217 cause mortality benefits associated management requirements adverse effect profile xlink "> schizophrenia pronounced geographic heterogeneity alleviating schizophrenia symptoms historically underutilized clozapine characterize clozapine utilization us medicaid recipients population (&# 8722 poor treatment adherence patterns previously identified 2015 &# 8722 corrected clozapine use clozapine use adjusted pronounced state variation us medicare patients pronounced state medicare patients clozapine use resistant schizophrenia level variation substance use training reform steady decrease spectrum disorders south dakota prescribed significantly practical solutions inadequate training education interventions demonstrated effectiveness 9 %) |
| status_str | publishedVersion |
| title | Large state-wide variation (10.2-fold) in number of clozapine prescriptions per thousand Medicare Part D enrollees in 2016 <sup>a</sup> indicates ≥1.50 SD (19.2) from the mean (34.8), which is denoted by the dotted line. <sup>b</sup> indicates ≥1.96 SD from the mean. |
| title_full | Large state-wide variation (10.2-fold) in number of clozapine prescriptions per thousand Medicare Part D enrollees in 2016 <sup>a</sup> indicates ≥1.50 SD (19.2) from the mean (34.8), which is denoted by the dotted line. <sup>b</sup> indicates ≥1.96 SD from the mean. |
| title_fullStr | Large state-wide variation (10.2-fold) in number of clozapine prescriptions per thousand Medicare Part D enrollees in 2016 <sup>a</sup> indicates ≥1.50 SD (19.2) from the mean (34.8), which is denoted by the dotted line. <sup>b</sup> indicates ≥1.96 SD from the mean. |
| title_full_unstemmed | Large state-wide variation (10.2-fold) in number of clozapine prescriptions per thousand Medicare Part D enrollees in 2016 <sup>a</sup> indicates ≥1.50 SD (19.2) from the mean (34.8), which is denoted by the dotted line. <sup>b</sup> indicates ≥1.96 SD from the mean. |
| title_short | Large state-wide variation (10.2-fold) in number of clozapine prescriptions per thousand Medicare Part D enrollees in 2016 <sup>a</sup> indicates ≥1.50 SD (19.2) from the mean (34.8), which is denoted by the dotted line. <sup>b</sup> indicates ≥1.96 SD from the mean. |
| title_sort | Large state-wide variation (10.2-fold) in number of clozapine prescriptions per thousand Medicare Part D enrollees in 2016 <sup>a</sup> indicates ≥1.50 SD (19.2) from the mean (34.8), which is denoted by the dotted line. <sup>b</sup> indicates ≥1.96 SD from the mean. |
| topic | Genetics Immunology Cancer Mental Health Environmental Sciences not elsewhere classified underutilization &# 8212 substantial economic burden spending (&# 8722 reduced suicide ideation medication &# 8217 cause mortality benefits associated management requirements adverse effect profile xlink "> schizophrenia pronounced geographic heterogeneity alleviating schizophrenia symptoms historically underutilized clozapine characterize clozapine utilization us medicaid recipients population (&# 8722 poor treatment adherence patterns previously identified 2015 &# 8722 corrected clozapine use clozapine use adjusted pronounced state variation us medicare patients pronounced state medicare patients clozapine use resistant schizophrenia level variation substance use training reform steady decrease spectrum disorders south dakota prescribed significantly practical solutions inadequate training education interventions demonstrated effectiveness 9 %) |