Hepatotoxicity of Three Common Liquid Crystal Monomers in Mus musculus: Differentiation of Actions Across Different Receptors and Pathways

Liquid crystal monomers (LCMs) of different chemical structures were widely detected in various environmental matrices. However, their health risk evaluation is lacking. Herein, three representative LCMs were selected from 74 LCM candidates upon literature review and acute cytotoxicity evaluation, t...

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Bibliographic Details
Main Author:	Zhichao Zhang (530603) (author)
Other Authors:	Shengjie Yuan (4541050) (author), Zhongchao Yang (20552440) (author), Yafeng Liu (192716) (author), Su Liu (1965895) (author), Ling Chen (25698) (author), Bing Wu (172312) (author)
Published:	2025
Subjects:	Biochemistry Cell Biology Genetics Inorganic Chemistry Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified Information Systems not elsewhere classified various environmental matrices study provides references histopathological results showed health risk evaluation fatty liver caused farnesoid x receptor aryl hydrocarbon receptor alanine aminotransferase levels acute cytotoxicity evaluation circadian clock homeostasis priority control lcms whereas 5ocb increased meo3bch promoted inflammation different chemical structures three representative lcms dtmdpb induced hepatotoxicity different structures three lcms induced hepatomegaly circadian rhythm widely detected mus musculus meo3bch decreased investigate hepatotoxicity ascorbic acid antioxidant pathways activated receptors 50 μg 42 days
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Hepatotoxicity of Three Common Liquid Crystal Monomers in Mus musculus: Differentiation of Actions Across Different Receptors and Pathways

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