Prediction of model compartments by MaxComp and its comparison with the ground truth on H1-hESC Chr15 and Chr18

<p>(A) The experimental profile obtained from the Hi-C-based principal component analysis and the compartment profile predicted by MaxComp of 500 modeled structures of Chr15. (B) The experimental profile obtained from the Hi-C-based principal component analysis and the compartment profile pred...

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Bibliographic Details
Main Author:	Yuxiang Zhan (11859404) (author)
Other Authors:	Francesco Musella (21417414) (author), Frank Alber (57158) (author)
Published:	2025
Subjects:	Cell Biology Genetics Molecular Biology Immunology Cancer Hematology Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified geometric principles alone 3d geometric considerations 3d chromosome structure two structural compartments distinct chromatin compartments div >< p compartment preferentially interact understanding chromatin compartmentalization chromatin regions within cell chromatin compartments b </ b chromatin regions </ b 3d coordinates defining compartments compartments based unsupervised method transcriptionally active transcriptional activity traditionally identified results show population average optimally partition opposite compartment omics imaging nuclear microenvironment new framework multiplexed fish cut problem covariance matrices compartment organization compartment annotations cell variations cell variability cell level c data broadly corresponding
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Prediction of model compartments by MaxComp and its comparison with the ground truth on H1-hESC Chr15 and Chr18

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