Diagnostic Model of IPF and sarcopenia.
<p>A-b. Variable locus diagram (A) and diagnostic model diagram (B) of LASSO regression model of idiopathic pulmonary fibrosis training set; C-d. Variable locus diagram (C) and diagnostic model diagram (D) of LASSO regression model for sarcopenia training set. At Least Absolute Shrinkage and S...
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2025
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| _version_ | 1852014373113954304 |
|---|---|
| author | Lanying Shen (22755930) |
| author2 | Zihan Yi (9467425) Jiahao Liu (2398594) Yinghua Ying (4333828) Yue Hu (201714) |
| author2_role | author author author author |
| author_facet | Lanying Shen (22755930) Zihan Yi (9467425) Jiahao Liu (2398594) Yinghua Ying (4333828) Yue Hu (201714) |
| author_role | author |
| dc.creator.none.fl_str_mv | Lanying Shen (22755930) Zihan Yi (9467425) Jiahao Liu (2398594) Yinghua Ying (4333828) Yue Hu (201714) |
| dc.date.none.fl_str_mv | 2025-12-01T18:37:30Z |
| dc.identifier.none.fl_str_mv | 10.1371/journal.pone.0335067.g011 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/figure/Diagnostic_Model_of_IPF_and_sarcopenia_/30754887 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Medicine Microbiology Cell Biology Genetics Molecular Biology Mental Health Infectious Diseases Biological Sciences not elsewhere classified weighted gene co risk assessment strategies multiple biological processes least absolute shrinkage immune cell populations idiopathic pulmonary fibrosis functional enrichment analyses expression network analysis examine immune infiltration could significantly improve amino acid metabolism xenobiotic metabolism pathways interrelated molecular pathways protein &# 8211 related crosstalk genes categorize associated pathways key genes associated construct diagnostic models lasso regression identified identifying er stress signaling pathways substantially associated protein interaction often associated diagnostic biomarkers xlink "> therapeutic targets study aimed sptssa </ selection operator response mechanism kyoto encyclopedia idi1 </ gstk1 </ foxo1 </ er stress endoplasmic reticulum early detection cibersort method cellular dysfunction |
| dc.title.none.fl_str_mv | Diagnostic Model of IPF and sarcopenia. |
| dc.type.none.fl_str_mv | Image Figure info:eu-repo/semantics/publishedVersion image |
| description | <p>A-b. Variable locus diagram (A) and diagnostic model diagram (B) of LASSO regression model of idiopathic pulmonary fibrosis training set; C-d. Variable locus diagram (C) and diagnostic model diagram (D) of LASSO regression model for sarcopenia training set. At Least Absolute Shrinkage and Selection Operator. ERSRCGs, Endoplasmic Reticulum Stress-Related Crosstalk Genes; IPFMGs, Idiopathic Pulmonary Fibrosis Model Genes; SMGs, Sarcopenia Model Genes.</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_ed0ddb754644ca4dfd762ec8b2d9d269 |
| identifier_str_mv | 10.1371/journal.pone.0335067.g011 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/30754887 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Diagnostic Model of IPF and sarcopenia.Lanying Shen (22755930)Zihan Yi (9467425)Jiahao Liu (2398594)Yinghua Ying (4333828)Yue Hu (201714)MedicineMicrobiologyCell BiologyGeneticsMolecular BiologyMental HealthInfectious DiseasesBiological Sciences not elsewhere classifiedweighted gene corisk assessment strategiesmultiple biological processesleast absolute shrinkageimmune cell populationsidiopathic pulmonary fibrosisfunctional enrichment analysesexpression network analysisexamine immune infiltrationcould significantly improveamino acid metabolismxenobiotic metabolism pathwaysinterrelated molecular pathwaysprotein &# 8211related crosstalk genescategorize associated pathwayskey genes associatedconstruct diagnostic modelslasso regression identifiedidentifying er stresssignaling pathwayssubstantially associatedprotein interactionoften associateddiagnostic biomarkersxlink ">therapeutic targetsstudy aimedsptssa </selection operatorresponse mechanismkyoto encyclopediaidi1 </gstk1 </foxo1 </er stressendoplasmic reticulumearly detectioncibersort methodcellular dysfunction<p>A-b. Variable locus diagram (A) and diagnostic model diagram (B) of LASSO regression model of idiopathic pulmonary fibrosis training set; C-d. Variable locus diagram (C) and diagnostic model diagram (D) of LASSO regression model for sarcopenia training set. At Least Absolute Shrinkage and Selection Operator. ERSRCGs, Endoplasmic Reticulum Stress-Related Crosstalk Genes; IPFMGs, Idiopathic Pulmonary Fibrosis Model Genes; SMGs, Sarcopenia Model Genes.</p>2025-12-01T18:37:30ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1371/journal.pone.0335067.g011https://figshare.com/articles/figure/Diagnostic_Model_of_IPF_and_sarcopenia_/30754887CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/307548872025-12-01T18:37:30Z |
| spellingShingle | Diagnostic Model of IPF and sarcopenia. Lanying Shen (22755930) Medicine Microbiology Cell Biology Genetics Molecular Biology Mental Health Infectious Diseases Biological Sciences not elsewhere classified weighted gene co risk assessment strategies multiple biological processes least absolute shrinkage immune cell populations idiopathic pulmonary fibrosis functional enrichment analyses expression network analysis examine immune infiltration could significantly improve amino acid metabolism xenobiotic metabolism pathways interrelated molecular pathways protein &# 8211 related crosstalk genes categorize associated pathways key genes associated construct diagnostic models lasso regression identified identifying er stress signaling pathways substantially associated protein interaction often associated diagnostic biomarkers xlink "> therapeutic targets study aimed sptssa </ selection operator response mechanism kyoto encyclopedia idi1 </ gstk1 </ foxo1 </ er stress endoplasmic reticulum early detection cibersort method cellular dysfunction |
| status_str | publishedVersion |
| title | Diagnostic Model of IPF and sarcopenia. |
| title_full | Diagnostic Model of IPF and sarcopenia. |
| title_fullStr | Diagnostic Model of IPF and sarcopenia. |
| title_full_unstemmed | Diagnostic Model of IPF and sarcopenia. |
| title_short | Diagnostic Model of IPF and sarcopenia. |
| title_sort | Diagnostic Model of IPF and sarcopenia. |
| topic | Medicine Microbiology Cell Biology Genetics Molecular Biology Mental Health Infectious Diseases Biological Sciences not elsewhere classified weighted gene co risk assessment strategies multiple biological processes least absolute shrinkage immune cell populations idiopathic pulmonary fibrosis functional enrichment analyses expression network analysis examine immune infiltration could significantly improve amino acid metabolism xenobiotic metabolism pathways interrelated molecular pathways protein &# 8211 related crosstalk genes categorize associated pathways key genes associated construct diagnostic models lasso regression identified identifying er stress signaling pathways substantially associated protein interaction often associated diagnostic biomarkers xlink "> therapeutic targets study aimed sptssa </ selection operator response mechanism kyoto encyclopedia idi1 </ gstk1 </ foxo1 </ er stress endoplasmic reticulum early detection cibersort method cellular dysfunction |