Quantitative Proteomic and Metabolomic Profiling Reveals Altered Purine Metabolism in Acute Kidney Injury after On-Pump Coronary Artery Bypass Graft

Acute kidney injury (AKI) is a frequent complication following on-pump coronary artery bypass graft surgery (CABG). To better investigate the effect of CABG on kidney function and the pathological process of AKI during the operation, the urine metabolic and protein signatures of four time points in...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Mindi Zhao (5543243) (author)
مؤلفون آخرون:	Xiaoyan Liu (158152) (author), Huawei Gao (845174) (author), Quaner Wang (21245570) (author), Zhengguang Guo (426323) (author), Yan Yang (33204) (author), Meice Tian (21586913) (author), Xianqiang Wang (477346) (author), Liqing Wang (188282) (author), Wei Sun (93580) (author), Chuanbao Li (1853710) (author)
منشور في:	2025
الموضوعات:	Biochemistry Medicine Cell Biology Genetics Physiology Developmental Biology Marine Biology Hematology Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified postoperative renal injury good predicting performance frequent complication following four time points proteomic data revealed protein catabolism pathway acute kidney injury 55 postoperative aki panel could play aki patients throughout quantitative proteomic protein signatures kidney function aki patients aki cohorts using high urine metabolic urinary metabolomics two proteins two metabolites study helps significant role reveal changes research suggests recovery process preoperative urine pattern recognition pathological process may help functional annotation distinguishing akis better investigate akis prior
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Quantitative Proteomic and Metabolomic Profiling Reveals Altered Purine Metabolism in Acute Kidney Injury after On-Pump Coronary Artery Bypass Graft

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