Order parameters versus temperature for amylase tasks:

Order parameters versus temperature for amylase tasks:

<p>mean score and variance of scores versus temperature after initial transient, i.e., at steady-state oscillatory BADASS behavior. Markers come from BADASS runs, and lines are fits using Eqs 5–7 in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1013119#pcbi...

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Bibliographic Details
Main Author: Carlos A. Gomez-Uribe (21492788) (author)
Other Authors: Japheth Gado (21492791) (author), Meiirbek Islamov (9733301) (author)
Published: 2025
Subjects:
Biophysics
Biochemistry
Evolutionary Biology
Biological Sciences not elsewhere classified
protein engineering approach
prevent premature convergence
large language model
innovative optimization algorithm
dynamically adjusting temperature
combining evolutionary data
sequences containing mutations
amino acid sequences
div >< p
badass may generalize
badass efficiently explores
loop </ p
000 sequences identified
experimental fitness measurements
generate diverse high
predict fitness landscapes
b </ b
</ b
000 sequences
fitness sequences
experimental labels
designing diverse
design sequences
000 ).
badass exceed
predicted fitness
underlying mechanism
top 1
sequence spaces
positions entirely
performance proteins
new semi
mutation energies
machine learning
every cutoff
directed evolution
alternative models
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