RSK inhibitors suppress ORF45-induced Filamin A phosphorylation.

<p>The solvent DMSO, 10 μM BI-D1870 or 10 μM SL0101 was added to ORF45-overexpressing HEK293 cells (A), iSLK.Bac16 cells undergoing Dox + NaB-induced lytic reactivation (B) and HEK293 cells infected with Bac16 virions (MOI = 10) (C) for 24 h, the cells were collected and the whole cell extract...

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Hlavní autor:	Xiaojuan Li (351842) (author)
Další autoři:	Li Quan (177024) (author), Rihong Zhou (22676690) (author), Xiangpeng Liu (17898881) (author), Ronit Sarid (186795) (author), Ersheng Kuang (129028) (author)
Vydáno:	2025
Témata:	Microbiology Cell Biology Molecular Biology Biotechnology Immunology Developmental Biology Cancer Infectious Diseases Virology s2152a knockin abolish primary effusion lymphoma multicentric castleman disease kaposi &# 8217 mediated viral infection infected adherent cells differentiated b cells sequential cell detachment mediated kshv transmission kshv lytic replication adherent cells lytic replication viral transmission kshv transmission cell detachment b lymphocytes lytic cycle cell transmission taken together results demonstrated radically support natural donors key role key regulator etiological agent dependent manner cell contact cell adhesion associated herpesvirus
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RSK inhibitors suppress ORF45-induced Filamin A phosphorylation.

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