Effects of receptor blockers on VO-induced hypertrophy in published experiments and the calibrated model.

<p>a) Simulations of β blockers (βB) at both early and late stages of VO, simulations (boxplots) were equally likely to predict increases or decreases, with no net effect on average. MR experiments in dogs (circles) [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal...

Full description

Saved in:

Bibliographic Details
Main Author:	Johane H. Bracamonte (12883844) (author)
Other Authors:	Lionel Watkins (21101254) (author), Betty Pat (15336130) (author), Louis J. Dell’Italia (8770514) (author), Jeffrey J. Saucerman (8131425) (author), Jeffrey W. Holmes (6087089) (author)
Published:	2025
Subjects:	Medicine Biological Sciences not elsewhere classified Information Systems not elsewhere classified treat heart failure provide significant recovery myocardial tissue stretch mitral valve repair increased myocyte strain calibrated model predicts based network model intracellular signaling network compensatory neurohormonal responses alters mechanical loading ventricular volume overload experimental volume overload cardiac hypertrophy driven mechanical loading overload hypertrophy volume overload neurohormonal response hypertrophic signaling expected responses cardiac function mostly driven eccentric hypertrophy driven primarily treated according time course questions remain quantitative predictions promising approach potential interventions optimal timing operatively despite observation contrasts multiple studies left ventricle known structure knowledge gap integrate information initial increase including infusion hypertrophic process experimental vo current guidelines common perception combine data better understanding better personalize bayesian approach 70 studies 43 studies
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!

Effects of receptor blockers on VO-induced hypertrophy in published experiments and the calibrated model.

Similar Items