Post-hoc planned contrasts with an adjusted mean difference for motor and cognitive performance outcomes between tasks in the OA group.

Post-hoc planned contrasts with an adjusted mean difference for motor and cognitive performance outcomes between tasks in the OA group.

<p>Post-hoc planned contrasts with an adjusted mean difference for motor and cognitive performance outcomes between tasks in the OA group.</p>

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書目詳細資料
主要作者:	Soyoung Lee (36756) (author)
其他作者:	Ehyun Kim (22232014) (author), Dilinazi Duolikun (22232017) (author), Baekdong Cha (12913694) (author), Claudio L. Ferre (7304090) (author), Meryem Yücel (22232020) (author), Deepak Kumar (63095) (author)
出版:	2025
主題:	Neuroscience Physiology Sociology Mental Health Biological Sciences not elsewhere classified stride length (< step duration (< correct response rate stride length variability step duration variability right ventrolateral pfc left dorsomedial pfc prefrontal cortex function bilateral prefrontal cortex assess pfc activation div >< p 2 </ sup prefrontal cortex pfc activation greater activation higher variability significantly different oa ). knee osteoarthritis knee oa infrared spectroscopy gait alterations digit number cognitive task
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Post-hoc planned contrasts with an adjusted mean difference and effect size with 95% confidence intervals (CIs) for ΔHbO<sub>2</sub> in all PFC subregions in the OA group.
由: Soyoung Lee (36756)
出版: (2025)

ΔHbO<sub>2</sub> in each subregion of PFC during Serial 7 (S7), single-task walking (STW), and dual-task walking (DTW) in the OA group.
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Summary of multiple linear regression models determining the association between ΔHbO<sub>2</sub> and motor/cognitive performance outcomes after adjusting for age, sex, and BMI in the OA group. Only pairs of ΔHbO<sub>2</sub> and performance outcomes showing correlation coefficient (<i>r)</i> values greater than 0.2 were investigated. Bold indicates p < 0.05.
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Heatmap of the Pearson correlation coefficient (<i>r</i>) between ΔHbO<sub>2</sub> of each subregion and each performance outcome during single-task (STW/S7) and dual-task (DTW) in the OA group.
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Boxplots of performance outcomes during Serial 7 (S7), single-task walking (STW) and dual-task walking (DTW) in the OA group; †Medium effect size (<i>d</i>); ‡Large effect size (<i>d</i>).
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Participant characteristics.
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Probe design covering bilateral prefrontal cortex (PFC) areas.
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(A) Experimental protocol of Serial 7 subtraction (S7), single-task walking (STW), and dual-task walking (DTW) (B) Experimental setup during STW.
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Table 1_Cutaneous sensory symptoms and emotional regulation in non-clinical healthy students: a near-infrared spectroscopy study.docx
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(A) Barplot corresponding to the true positive rates obtained using the first task-related demixed principal components as a linear classifier to classify trials by task (Endogenous attention, blue; Exogenous attention, green; Memory saccade, red) (1-way ANOVA, task as main factor, on dPC1: <i>p</i> = 9.6184<i>e</i> − 10: Exo versus Endo: post-hoc Bonferroni: <i>p</i> > 0.05; Exo versus Mem: post-hoc Bonferroni: <i>p</i> = 1.8546<i>e</i> − 8; Endo versus Mem: post-hoc Bonferroni: <i>p</i> = 8.6775<i>e</i> − 9; 1-way ANOVA, task as main factor, on dPC2: <i>p</i> = 4.0943<i>e</i> − 6, Exo versus Endo: post-hoc Bonferroni: <i>p</i> > 0.05; Exo versus Mem: post-hoc Bonferroni: <i>p</i> = 0.0011; Endo versus Mem: post-hoc Bonferroni: <i>p</i> = 3.1361<i>e</i> − 6).
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Demixed PCA unmixes task and spatial sources related to variance.
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Demixed PCA unmixes task and independent sources related to variance.
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Spatial tuning of mixed-selectivity cells.
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Mixed selectivity corresponds to the ability of a neuronal population to encode simultaneously independent sources of information: (A) Firing rate of a representative MUA aligned on the cue (200 ms before the cue onset to 1,000 ms after the cue onset) in exogenous task (blue), endogenous task (green) and memory guided saccade task (red) for preferred (solid line) and non-preferred (dash line) position.
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Description of the tasks and main behavioral results.
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Distribution of weights attributed to the different units in the first position-related dPC as a function of the first task-related dPC, for both SUAs (left) and MUAs (right).
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Demixed PCA unmixes task and spatial sources related to variance in SUAs.
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All as in Fig 4, except that dPCA is performed on a time interval running from (A1 to D1) 0–500 ms after cue presentation; (A2 to D2) −500 to 0 Pre-target presentation and (A3 to D3) 0–500 ms Post-target presentation.
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Raster plots of representative MUA and SUA examples.
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Projection of MUA onto the first and second demixed principal components extracted with a dPCA analysis.
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Demixed PCA unmixes task and independent sources related to variance in SUAs.
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Projection of MUA population activity onto the first and second principal components extracted with a PCA analysis.
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Spatial tuning of mixed-selectivity cells.
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(A) MUA: Top row: Venn diagram representing the proportion of cells showing a spatial tuning in each of the three tasks.
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(A) MUA example of task selectivity (left), position selectivity (middle) and mixed-selectivity (right).
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(A) Firing rate of a representative MUA (same as in Fig 2) aligned to target onset (400 ms before target onset to 600 ms after target onset) averaged across trials of the exogenous attention task (blue), the endogenous attention task (green) and the memory guided saccade task (red) for preferred (solid line) and least-preferred (dash line) positions.
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