Characteristic Flavaglines with Therapeutic Potential for Ischemic Stroke from <i>Aglaia perviridis</i>

Characteristic Flavaglines with Therapeutic Potential for Ischemic Stroke from <i>Aglaia perviridis</i>

To investigate the material basis and mechanisms underlying the therapeutic effects of <i>Aglaia perviridis</i> on ischemic stroke, the anti-ischemic stroke activities of various crude extracts and derived compounds were evaluated using both middle cerebral artery occlusion/reperfusion (...

Volledige beschrijving

Bewaard in:

Bibliografische gegevens
Hoofdauteur:	Yan-Ping Zhang (432349) (author)
Andere auteurs:	Ling Li (38566) (author), Qian-Qian Yin (453477) (author), Ye-Wen Jia (22683815) (author), Ming-Xia Fang (21340067) (author), Qing-Qi Meng (21340070) (author), Yue Hou (2562085) (author), Jin-Le Hao (22683818) (author), Bin Lin (302181) (author), Di Zhou (126052) (author), Ning Li (45258) (author)
Gepubliceerd in:	2025
Onderwerpen:	Biochemistry Medicine Cell Biology Pharmacology Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified various crude extracts significant antineuroinflammatory activity potently inhibited lps performance liquid chromatography induced nitric oxide ethyl acetate extract electronic circular dichroism alleviated cerebral edema >] furan backbone 21 ± 3 04 ± 1 nmr ), high potential biosynthetic pathways characterized using high aglaia perviridis </ 6 </ b 5 </ b 1 </ b ischemic stroke activities contains total flavaglines comprehensive phytochemical analysis 50 </ sub 2 microglia models ms ), acd 2 </ b perviridis </ b </ ischemic stroke ape ), therapeutic potential rat models evaluated using 2 cells therapeutic effects structure elucidator probability analysis mechanisms underlying material basis hplc ). characteristic flavaglines benz [< ape led 10 μm
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items

Characteristic Flavaglines with Therapeutic Potential for Ischemic Stroke from <i>Aglaia perviridis</i>
door: Yan-Ping Zhang (432349)
Gepubliceerd in: (2025)

Characteristic Flavaglines with Therapeutic Potential for Ischemic Stroke from <i>Aglaia perviridis</i>
door: Yan-Ping Zhang (432349)
Gepubliceerd in: (2025)

Characteristic Flavaglines with Therapeutic Potential for Ischemic Stroke from <i>Aglaia perviridis</i>
door: Yan-Ping Zhang (432349)
Gepubliceerd in: (2025)

Characteristic Flavaglines with Therapeutic Potential for Ischemic Stroke from <i>Aglaia perviridis</i>
door: Yan-Ping Zhang (432349)
Gepubliceerd in: (2025)

Characteristic Flavaglines with Therapeutic Potential for Ischemic Stroke from <i>Aglaia perviridis</i>
door: Yan-Ping Zhang (432349)
Gepubliceerd in: (2025)

Characteristic Flavaglines with Therapeutic Potential for Ischemic Stroke from <i>Aglaia perviridis</i>
door: Yan-Ping Zhang (432349)
Gepubliceerd in: (2025)

Characteristic Flavaglines with Therapeutic Potential for Ischemic Stroke from <i>Aglaia perviridis</i>
door: Yan-Ping Zhang (432349)
Gepubliceerd in: (2025)

Characteristic Flavaglines with Therapeutic Potential for Ischemic Stroke from <i>Aglaia perviridis</i>
door: Yan-Ping Zhang (432349)
Gepubliceerd in: (2025)

Table 1_Subacute edema progression after acute ischemic stroke: impact of intravenous alteplase administration and reperfusion degree.docx
door: Wiktor Olszewski (22679396)
Gepubliceerd in: (2025)

Data Sheet 1_Inflammatory biomarkers in cerebral venous thrombosis versus ischemic stroke: a network meta-analysis.pdf
door: Xinlong Shen (22686395)
Gepubliceerd in: (2025)

Table 1_Effect of general anesthesia vs. local anesthesia and collateral status on outcomes in anterior circulation occlusion.docx
door: Guojie Chen (11804164)
Gepubliceerd in: (2025)

Image 1_Effect of general anesthesia vs. local anesthesia and collateral status on outcomes in anterior circulation occlusion.jpeg
door: Guojie Chen (11804164)
Gepubliceerd in: (2025)

Parameter values for four-pathway synaptic plasticity model.
door: Nicholas Hananeia (22683665)
Gepubliceerd in: (2025)

Ion channels and membrane properties.
door: Nicholas Hananeia (22683665)
Gepubliceerd in: (2025)

Distal LTP induced by simulated rMS is sustained by sodium dendritic spikes but less affected by inhibition than local electrical stimulation.
door: Nicholas Hananeia (22683665)
Gepubliceerd in: (2025)

Voltage traces from local electrical and rMS TBS, recorded at the soma and distal apical tuft, account for the outcomes of synaptic plasticity.
door: Nicholas Hananeia (22683665)
Gepubliceerd in: (2025)

The synaptic plasticity model reproduces distal LTP for local electric TBS and predicts proximal and distal LTP for rMS TBS.
door: Nicholas Hananeia (22683665)
Gepubliceerd in: (2025)

Pharmacology in silico: rMS-induced LTP depends on dendritic sodium and calcium through voltage-gated calcium channels, as well as synaptic NMDA channels.
door: Nicholas Hananeia (22683665)
Gepubliceerd in: (2025)

Presynaptic and postsynaptic weights change monotonically linearly over stimulus duration.
door: Nicholas Hananeia (22683665)
Gepubliceerd in: (2025)

The modelling framework for synaptic plasticity replicates proximal LTP induced by 10 Hz rMS protocol and predicts increasing LTP with higher stimulation frequency.
door: Nicholas Hananeia (22683665)
Gepubliceerd in: (2025)

Unifying four-pathway model of long-term synaptic plasticity reproduces frequency dependence of synaptic changes in hippocampal CA1 pyramidal cells evoked by local electrical Schaffer collateral stimulation
door: Nicholas Hananeia (22683665)
Gepubliceerd in: (2025)

Modelling framework for TMS-induced long-term synaptic plasticity.
door: Nicholas Hananeia (22683665)
Gepubliceerd in: (2025)

HippoUnit test error scores show the validity of the CA1 pyramidal cell model.
door: Nicholas Hananeia (22683665)
Gepubliceerd in: (2025)

Schematic of added myelinated axon.
door: Nicholas Hananeia (22683665)
Gepubliceerd in: (2025)

TMS pulse propagates beginning in the axon terminal, subsequently activating soma and dendrites.
door: Nicholas Hananeia (22683665)
Gepubliceerd in: (2025)

Plasticity model reproduces an additional synaptic plasticity paradigm using pairings of presynaptic spikes or bursts of spikes with postsnyaptic spikes or bursts of spikes.
door: Nicholas Hananeia (22683665)
Gepubliceerd in: (2025)

Tonic inhibition reduces LTP amplitude but maintains proximal potentiation and frequency dependence.
door: Nicholas Hananeia (22683665)
Gepubliceerd in: (2025)

Plasticity model shows continued linear increases in LTP induction at higher frequencies.
door: Nicholas Hananeia (22683665)
Gepubliceerd in: (2025)

LTP induced by 10 Hz rMS rapidly increases after crossing firing threshold, but quickly saturates.
door: Nicholas Hananeia (22683665)
Gepubliceerd in: (2025)

Biphasic stimulus shows different frequency dependence to monophasic stimulus.
door: Nicholas Hananeia (22683665)
Gepubliceerd in: (2025)

Medication-inclusive multivariable logistic regression for MAFLD.
door: Zienab M. Saad (22676502)
Gepubliceerd in: (2025)

Multivariable logistic regression models for MAFLD predictors.
door: Zienab M. Saad (22676502)
Gepubliceerd in: (2025)

Liver Fibrosis Characteristics by CKD Stage in MAFLD Patients (n = 64).
door: Zienab M. Saad (22676502)
Gepubliceerd in: (2025)

Liver Stiffness and Fibrosis Grading by MAFLD Status.
door: Zienab M. Saad (22676502)
Gepubliceerd in: (2025)

Comparison of Non-invasive Liver Fibrosis Scores.
door: Zienab M. Saad (22676502)
Gepubliceerd in: (2025)

Demographic and Clinical Characteristics of Study Participants.
door: Zienab M. Saad (22676502)
Gepubliceerd in: (2025)

Proposed pathophysiological crosstalk between MAFLD and CKD.
door: Zienab M. Saad (22676502)
Gepubliceerd in: (2025)

Receiver operating characteristic (ROC) curve analysis comparing the performance of non-invasive fibrosis scores in MAFLD patients.
door: Zienab M. Saad (22676502)
Gepubliceerd in: (2025)

Stratification of Liver Stiffness according to eGFR in the MAFLD group.
door: Zienab M. Saad (22676502)
Gepubliceerd in: (2025)

A. Violin plots showing eGFR distribution in MAFLD (red) vs. non-MAFLD (blue) groups.
door: Zienab M. Saad (22676502)
Gepubliceerd in: (2025)

Cannot write session to /tmp/vufind_sessions/sess_2njprgrt6koa2lvg11o957gpi4