Overexpressing RP11-502I4.3 inhibited the trend of angiogenesis in rats.

(A) Hematoxylin and eosin staining of retinal sections of the control group, diabetes mellitus (DM) group, DM + overexpression (OE)-normal control (NC) group, and DM + OE-RP11-502I4.3 group. (B) Retinal layer thickness and (C) The number of retinal ganglion cells (RGCs) o...

وصف كامل

محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Lan Zeng (638254) (author)
مؤلفون آخرون:	Yuhao Wu (4633129) (author), Lijuan Zhu (1315161) (author), Junhao He (11372681) (author), Yuan Yuan (25702) (author), Xiaocong Wang (2829053) (author), Kai Tang (138245) (author), Wei Tan (123562) (author)
منشور في:	2025
الموضوعات:	Biochemistry Medicine Cell Biology Molecular Biology Physiology Science Policy Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified tube formation ability retinal layer thickness retinal ganglion cells outer nuclear layers div >< p structural alterations related normal glucose conditions might inhibit retinopathy stimulated hrmecs compared decreased vegf levels targeting long non induced diabetic rats long non diabetic retinopathy diabetic rats high glucose vegf ). treated hrmecs hrmecs ). induced angiogenesis structural changes significantly higher reduced count proliferative activity migration count leading cause control group coding rna assessed differences analysis revealed acellular capillaries 3 </
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

الوصف
الملخص:	<p>(A) Hematoxylin and eosin staining of retinal sections of the control group, diabetes mellitus (DM) group, DM + overexpression (OE)-normal control (NC) group, and DM + OE-<i>RP11-502I4.3</i> group. (B) Retinal layer thickness and (C) The number of retinal ganglion cells (RGCs) of four groups. The above experiments were repeated three times in parallel. * <i>p</i> < 0.05. (D) Periodic acid-Schiff staining of retinas of four groups. The acellular capillaries are shown by black arrows. (E) Change of acellular capillary of four groups. The experiment was repeated three times in parallel. * <i>p</i> < 0.05. (F) The expression of <i>vascular endothelial growth factor (VEGF)</i> in rats after overexpressing the <i>RP11-502I4.3</i> was analyzed by quantitative real-time polymerase chain reaction. The experiment was repeated three times in parallel. * <i>p</i> < 0.05.</p>

Overexpressing <i>RP11-502I4.3</i> inhibited the trend of angiogenesis in rats.

مواد مشابهة