Overexpressing RP11-502I4.3 inhibited the trend of angiogenesis in rats.

(A) Hematoxylin and eosin staining of retinal sections of the control group, diabetes mellitus (DM) group, DM + overexpression (OE)-normal control (NC) group, and DM + OE-RP11-502I4.3 group. (B) Retinal layer thickness and (C) The number of retinal ganglion cells (RGCs) o...

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Main Author:	Lan Zeng (638254) (author)
Other Authors:	Yuhao Wu (4633129) (author), Lijuan Zhu (1315161) (author), Junhao He (11372681) (author), Yuan Yuan (25702) (author), Xiaocong Wang (2829053) (author), Kai Tang (138245) (author), Wei Tan (123562) (author)
Published:	2025
Subjects:	Biochemistry Medicine Cell Biology Molecular Biology Physiology Science Policy Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified tube formation ability retinal layer thickness retinal ganglion cells outer nuclear layers div >< p structural alterations related normal glucose conditions might inhibit retinopathy stimulated hrmecs compared decreased vegf levels targeting long non induced diabetic rats long non diabetic retinopathy diabetic rats high glucose vegf ). treated hrmecs hrmecs ). induced angiogenesis structural changes significantly higher reduced count proliferative activity migration count leading cause control group coding rna assessed differences analysis revealed acellular capillaries 3 </
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Overexpressing <i>RP11-502I4.3</i> inhibited the trend of angiogenesis in rats.

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