Distribution of nAb titers in samples collected during the 2017 outbreak.

Distribution of nAb titers in samples collected during the 2017 outbreak.

<p><b>(A and B)</b> NT<sub>90</sub> titers were determined according to DENV1–4 reference serotypes (A) and sample collection site (B). Mean values for n = 47 (n = 21 Kathmandu, n = 26 Chitwan) with circles representing individual samples. Dashed lines represent the cut...

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Main Author: Sabita Prajapati (9094758) (author)
Other Authors: Annie Elong Ngono (20189570) (author), Melanie Mc Cauley (20189573) (author), Julia Timis (20189576) (author), Srijan Shrestha (9094764) (author), Anup Bastola (5368370) (author), Shrawan Kumar Mandal (20189579) (author), Sanjay Ray Yadav (9094776) (author), Rajindra Napit (9094761) (author), Meng Ling Moi (10748547) (author), Montarop Yamabhai (805516) (author), October M. Sessions (10961891) (author), Sujan Shresta (103224) (author), Krishna Das Manandhar (9094779) (author)
Published: 2024
Subjects:
Medicine
Microbiology
Neuroscience
Biotechnology
Ecology
Immunology
Infectious Diseases
Virology
Environmental Sciences not elsewhere classified
sup >+</ sup
serology analysis suggested
results provide evidence
expanded local surveillance
66 %); among
nepal since 2006
acute dengue infection
suspected denv infection
secondary denv infections
denv ns1 antigen
neutralizing serological profiles
47 sera tested
div >< p
58 %) samples
denv immunity within
circulating denv genotypes
nepal </ p
49 subjects assessed
2017 dengue season
multiple denv serotypes
2017 cohort study
47 subjects
multiple serotypes
dengue virus
across nepal
strains circulating
population immunity
neutralizing antibodies
genetic study
49 patients
4 serotypes
43 %)
40 %)
denv igm
specific elisas
past exposure
nepalese population
nearly 50
global population
genomic sequencing
genome sequencing
experiencing primary
envelope genes
effectively manage
dominant serotype
data suggest
central hospitals
borne flavivirus
also similar
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Summary:<p><b>(A and B)</b> NT<sub>90</sub> titers were determined according to DENV1–4 reference serotypes (A) and sample collection site (B). Mean values for n = 47 (n = 21 Kathmandu, n = 26 Chitwan) with circles representing individual samples. Dashed lines represent the cutoff value for nAb positivity (NT<sub>90</sub> = 40). Mean values were compared using the non-parametric Kruskal–Wallis test.</p>

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