Supplementary Figure S2 from Serologic Profiling Using an Epstein-Barr Virus Mammalian Expression Library Identifies EBNA1 IgA as a Prediagnostic Marker for Nasopharyngeal Carcinoma

<p>Detection of EBV-specific IgG in sera from incident NPC cases and healthy controls in the SCHS cohort. Heatmap depicting IgG heavy and light chain-specific (IgGH+L) detection values from 20 incident NPC case-control pairs and the data is represented similarly to Fig 2 with Fisher’s exact te...

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主要作者: Sarita Paudel (15047430) (author)
其他作者: Benjamin E. Warner (15047433) (author), Renwei Wang (15047436) (author), Jennifer Adams-Haduch (15047439) (author), Alex S. Reznik (15047442) (author), Jason Dou (15047445) (author), Yufei Huang (10791191) (author), Yu-Tang Gao (15047448) (author), Woon-Puay Koh (15047451) (author), Alan Bäckerholm (15047454) (author), Jian-Min Yuan (15047457) (author), Kathy H.Y. Shair (15047460) (author)
出版: 2025
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_version_ 1849927633756749824
author Sarita Paudel (15047430)
author2 Benjamin E. Warner (15047433)
Renwei Wang (15047436)
Jennifer Adams-Haduch (15047439)
Alex S. Reznik (15047442)
Jason Dou (15047445)
Yufei Huang (10791191)
Yu-Tang Gao (15047448)
Woon-Puay Koh (15047451)
Alan Bäckerholm (15047454)
Jian-Min Yuan (15047457)
Kathy H.Y. Shair (15047460)
author2_role author
author
author
author
author
author
author
author
author
author
author
author_facet Sarita Paudel (15047430)
Benjamin E. Warner (15047433)
Renwei Wang (15047436)
Jennifer Adams-Haduch (15047439)
Alex S. Reznik (15047442)
Jason Dou (15047445)
Yufei Huang (10791191)
Yu-Tang Gao (15047448)
Woon-Puay Koh (15047451)
Alan Bäckerholm (15047454)
Jian-Min Yuan (15047457)
Kathy H.Y. Shair (15047460)
author_role author
dc.creator.none.fl_str_mv Sarita Paudel (15047430)
Benjamin E. Warner (15047433)
Renwei Wang (15047436)
Jennifer Adams-Haduch (15047439)
Alex S. Reznik (15047442)
Jason Dou (15047445)
Yufei Huang (10791191)
Yu-Tang Gao (15047448)
Woon-Puay Koh (15047451)
Alan Bäckerholm (15047454)
Jian-Min Yuan (15047457)
Kathy H.Y. Shair (15047460)
dc.date.none.fl_str_mv 2025-11-25T12:49:06Z
dc.identifier.none.fl_str_mv 10.1158/1078-0432.30706517
dc.relation.none.fl_str_mv https://figshare.com/articles/figure/Supplementary_Figure_S2_from_Serologic_Profiling_Using_an_Epstein-Barr_Virus_Mammalian_Expression_Library_Identifies_EBNA1_IgA_as_a_Prediagnostic_Marker_for_Nasopharyngeal_Carcinoma/30706517
dc.rights.none.fl_str_mv CC BY
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Cancer
Cancer Biology
Cancer Detection and Diagnosis
Therapeutic Research and Development
Biomarkers
Cancer risk biomarkers
Serum biomarkers
Head, Neck & Oral Cancers
Translational Research
Viral Oncogenesis
Human tumor viruses
dc.title.none.fl_str_mv Supplementary Figure S2 from Serologic Profiling Using an Epstein-Barr Virus Mammalian Expression Library Identifies EBNA1 IgA as a Prediagnostic Marker for Nasopharyngeal Carcinoma
dc.type.none.fl_str_mv Image
Figure
info:eu-repo/semantics/publishedVersion
image
description <p>Detection of EBV-specific IgG in sera from incident NPC cases and healthy controls in the SCHS cohort. Heatmap depicting IgG heavy and light chain-specific (IgGH+L) detection values from 20 incident NPC case-control pairs and the data is represented similarly to Fig 2 with Fisher’s exact test identifying proteins (bolded) that discriminate case from controls and denoted *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001. IgGH+L represents total antibody responses because light chains common to all antibody isotypes are detected.</p>
eu_rights_str_mv openAccess
id Manara_f61f1c47f62b135e8e427076622c742e
identifier_str_mv 10.1158/1078-0432.30706517
network_acronym_str Manara
network_name_str ManaraRepo
oai_identifier_str oai:figshare.com:article/30706517
publishDate 2025
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repository.name.fl_str_mv
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rights_invalid_str_mv CC BY
spelling Supplementary Figure S2 from Serologic Profiling Using an Epstein-Barr Virus Mammalian Expression Library Identifies EBNA1 IgA as a Prediagnostic Marker for Nasopharyngeal CarcinomaSarita Paudel (15047430)Benjamin E. Warner (15047433)Renwei Wang (15047436)Jennifer Adams-Haduch (15047439)Alex S. Reznik (15047442)Jason Dou (15047445)Yufei Huang (10791191)Yu-Tang Gao (15047448)Woon-Puay Koh (15047451)Alan Bäckerholm (15047454)Jian-Min Yuan (15047457)Kathy H.Y. Shair (15047460)CancerCancer BiologyCancer Detection and DiagnosisTherapeutic Research and DevelopmentBiomarkersCancer risk biomarkersSerum biomarkersHead, Neck & Oral CancersTranslational ResearchViral OncogenesisHuman tumor viruses<p>Detection of EBV-specific IgG in sera from incident NPC cases and healthy controls in the SCHS cohort. Heatmap depicting IgG heavy and light chain-specific (IgGH+L) detection values from 20 incident NPC case-control pairs and the data is represented similarly to Fig 2 with Fisher’s exact test identifying proteins (bolded) that discriminate case from controls and denoted *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001. IgGH+L represents total antibody responses because light chains common to all antibody isotypes are detected.</p>2025-11-25T12:49:06ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1158/1078-0432.30706517https://figshare.com/articles/figure/Supplementary_Figure_S2_from_Serologic_Profiling_Using_an_Epstein-Barr_Virus_Mammalian_Expression_Library_Identifies_EBNA1_IgA_as_a_Prediagnostic_Marker_for_Nasopharyngeal_Carcinoma/30706517CC BYinfo:eu-repo/semantics/openAccessoai:figshare.com:article/307065172025-11-25T12:49:06Z
spellingShingle Supplementary Figure S2 from Serologic Profiling Using an Epstein-Barr Virus Mammalian Expression Library Identifies EBNA1 IgA as a Prediagnostic Marker for Nasopharyngeal Carcinoma
Sarita Paudel (15047430)
Cancer
Cancer Biology
Cancer Detection and Diagnosis
Therapeutic Research and Development
Biomarkers
Cancer risk biomarkers
Serum biomarkers
Head, Neck & Oral Cancers
Translational Research
Viral Oncogenesis
Human tumor viruses
status_str publishedVersion
title Supplementary Figure S2 from Serologic Profiling Using an Epstein-Barr Virus Mammalian Expression Library Identifies EBNA1 IgA as a Prediagnostic Marker for Nasopharyngeal Carcinoma
title_full Supplementary Figure S2 from Serologic Profiling Using an Epstein-Barr Virus Mammalian Expression Library Identifies EBNA1 IgA as a Prediagnostic Marker for Nasopharyngeal Carcinoma
title_fullStr Supplementary Figure S2 from Serologic Profiling Using an Epstein-Barr Virus Mammalian Expression Library Identifies EBNA1 IgA as a Prediagnostic Marker for Nasopharyngeal Carcinoma
title_full_unstemmed Supplementary Figure S2 from Serologic Profiling Using an Epstein-Barr Virus Mammalian Expression Library Identifies EBNA1 IgA as a Prediagnostic Marker for Nasopharyngeal Carcinoma
title_short Supplementary Figure S2 from Serologic Profiling Using an Epstein-Barr Virus Mammalian Expression Library Identifies EBNA1 IgA as a Prediagnostic Marker for Nasopharyngeal Carcinoma
title_sort Supplementary Figure S2 from Serologic Profiling Using an Epstein-Barr Virus Mammalian Expression Library Identifies EBNA1 IgA as a Prediagnostic Marker for Nasopharyngeal Carcinoma
topic Cancer
Cancer Biology
Cancer Detection and Diagnosis
Therapeutic Research and Development
Biomarkers
Cancer risk biomarkers
Serum biomarkers
Head, Neck & Oral Cancers
Translational Research
Viral Oncogenesis
Human tumor viruses