Image 3_Synthetic DNA co-immunization with vaccine-aligned common consensus nucleoprotein and hemagglutinin protects mice against lethal influenza infection with a single immunization.tif

Image 3_Synthetic DNA co-immunization with vaccine-aligned common consensus nucleoprotein and hemagglutinin protects mice against lethal influenza infection with a single immunization.tif

Introduction<p>There is an urgent need for influenza vaccine strategies that enhance protection against influenza virus drift and across different subtypes. The conserved viral nucleoprotein (NP) is the most abundant viral protein during replication, and a target for broadly protective cellula...

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主要作者: Ebony N. Gary (2019478) (author)
其他作者: Abigail R. Trachtman (21841544) (author), Dan Wang (34472) (author), Suman Bharti (9990011) (author), Ying Ye (72583) (author), Nicholas J. Tursi (10166063) (author), Martina Tomirotti (22686932) (author), Jillian Eisenhauer (21841538) (author), Jacqueline D. Chu (21841547) (author), David Custodio Zegarra (22686935) (author), Casey E. Hojecki (22686959) (author), Micki Zheng (22686962) (author), Jayamanna Wickramasinghe (4782693) (author), David B. Weiner (9579320) (author), Ami Patel (139999) (author)
出版: 2025
主题:
Genetic Immunology
influenza A virus
nucleoprotein
hemagglutinin
synthetic DNA
multivalent vaccine
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