Table 1_Potential spillover effect of eco-directed pharmaceutical disposal on pro-environmental disinfectant use among Chinese residents.docx
Background<p>The growing use of disinfectants has raised ecological concerns regarding disinfectants as emerging environmental contaminants. Given the similarities in environmental fate and discharge behavior between pharmaceuticals and disinfectants, ecopharmacovigilance (EPV) as a framework...
Uloženo v:
| Hlavní autor: | |
|---|---|
| Další autoři: | , |
| Vydáno: |
2025
|
| Témata: | |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
|
| _version_ | 1849927622648135680 |
|---|---|
| author | Xintong Chen (517562) |
| author2 | Yongxin Tong (22687583) Jun Wang (5906) |
| author2_role | author author |
| author_facet | Xintong Chen (517562) Yongxin Tong (22687583) Jun Wang (5906) |
| author_role | author |
| dc.creator.none.fl_str_mv | Xintong Chen (517562) Yongxin Tong (22687583) Jun Wang (5906) |
| dc.date.none.fl_str_mv | 2025-11-26T06:34:18Z |
| dc.identifier.none.fl_str_mv | 10.3389/fpubh.2025.1707924.s001 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/dataset/Table_1_Potential_spillover_effect_of_eco-directed_pharmaceutical_disposal_on_pro-environmental_disinfectant_use_among_Chinese_residents_docx/30718877 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Public Health and Health Services not elsewhere classified disinfection ecopharmacovigilance emerging contaminants environmental spillover knowledge-attitude-practice pharmaceutical emerging contaminants |
| dc.title.none.fl_str_mv | Table 1_Potential spillover effect of eco-directed pharmaceutical disposal on pro-environmental disinfectant use among Chinese residents.docx |
| dc.type.none.fl_str_mv | Dataset info:eu-repo/semantics/publishedVersion dataset |
| description | Background<p>The growing use of disinfectants has raised ecological concerns regarding disinfectants as emerging environmental contaminants. Given the similarities in environmental fate and discharge behavior between pharmaceuticals and disinfectants, ecopharmacovigilance (EPV) as a framework emphasizing eco-directed pharmaceutical use and disposal was previously proposed as a potential strategy to mitigate environmental emissions of disinfectants. This study investigated the likelihood of spillover between eco-directed pharmaceutical disposal and pro-environmental disinfectant use across knowledge, attitude, and practice (KAP) dimensions, and examine whether perceived similarity between pharmaceuticals and disinfectants mediated these spillover effects.</p>Methods<p>Using a sample of 1,002 Chinese residents, questionnaire-based KAP survey data were analyzed using regression analysis for spillover effect test. A bias-corrected non-parametric percentile Bootstrap test was employed to examine mediation effects.</p>Results<p>A one-unit increase in eco-directed pharmaceutical disposal improved the residents’ pro-environmental disinfectant use by 0.648, 0.782, and 0.791 units in KAP dimensions (p = 0.000), respectively, under the control of covariates. Similarity recognition exerted a significant mediating effect on the relationship between eco-directed pharmaceutical disposal and pro-environmental disinfectant use, with the effect size values of 0.168 (95% confidence interval [CI]: 0.130, 0.206), 0.107 (95% CI: 0.072, 0.142), and 0.079 (95% CI: 0.029, 0.128) across KAP dimensions, respectively.</p>Conclusion<p>Eco-directed pharmaceutical disposal might positively spill over to pro-environmental disinfectant use partially through indirect path of the perceived similarity, which further supports the feasibility of adopting EPV, a framework originally designed for pharmaceutical environmental risk management, for the remediation of disinfectant emerging contaminants.</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_f672bcbd6c47a49ef693a42663dc315e |
| identifier_str_mv | 10.3389/fpubh.2025.1707924.s001 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/30718877 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Table 1_Potential spillover effect of eco-directed pharmaceutical disposal on pro-environmental disinfectant use among Chinese residents.docxXintong Chen (517562)Yongxin Tong (22687583)Jun Wang (5906)Public Health and Health Services not elsewhere classifieddisinfectionecopharmacovigilanceemerging contaminantsenvironmental spilloverknowledge-attitude-practicepharmaceutical emerging contaminantsBackground<p>The growing use of disinfectants has raised ecological concerns regarding disinfectants as emerging environmental contaminants. Given the similarities in environmental fate and discharge behavior between pharmaceuticals and disinfectants, ecopharmacovigilance (EPV) as a framework emphasizing eco-directed pharmaceutical use and disposal was previously proposed as a potential strategy to mitigate environmental emissions of disinfectants. This study investigated the likelihood of spillover between eco-directed pharmaceutical disposal and pro-environmental disinfectant use across knowledge, attitude, and practice (KAP) dimensions, and examine whether perceived similarity between pharmaceuticals and disinfectants mediated these spillover effects.</p>Methods<p>Using a sample of 1,002 Chinese residents, questionnaire-based KAP survey data were analyzed using regression analysis for spillover effect test. A bias-corrected non-parametric percentile Bootstrap test was employed to examine mediation effects.</p>Results<p>A one-unit increase in eco-directed pharmaceutical disposal improved the residents’ pro-environmental disinfectant use by 0.648, 0.782, and 0.791 units in KAP dimensions (p = 0.000), respectively, under the control of covariates. Similarity recognition exerted a significant mediating effect on the relationship between eco-directed pharmaceutical disposal and pro-environmental disinfectant use, with the effect size values of 0.168 (95% confidence interval [CI]: 0.130, 0.206), 0.107 (95% CI: 0.072, 0.142), and 0.079 (95% CI: 0.029, 0.128) across KAP dimensions, respectively.</p>Conclusion<p>Eco-directed pharmaceutical disposal might positively spill over to pro-environmental disinfectant use partially through indirect path of the perceived similarity, which further supports the feasibility of adopting EPV, a framework originally designed for pharmaceutical environmental risk management, for the remediation of disinfectant emerging contaminants.</p>2025-11-26T06:34:18ZDatasetinfo:eu-repo/semantics/publishedVersiondataset10.3389/fpubh.2025.1707924.s001https://figshare.com/articles/dataset/Table_1_Potential_spillover_effect_of_eco-directed_pharmaceutical_disposal_on_pro-environmental_disinfectant_use_among_Chinese_residents_docx/30718877CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/307188772025-11-26T06:34:18Z |
| spellingShingle | Table 1_Potential spillover effect of eco-directed pharmaceutical disposal on pro-environmental disinfectant use among Chinese residents.docx Xintong Chen (517562) Public Health and Health Services not elsewhere classified disinfection ecopharmacovigilance emerging contaminants environmental spillover knowledge-attitude-practice pharmaceutical emerging contaminants |
| status_str | publishedVersion |
| title | Table 1_Potential spillover effect of eco-directed pharmaceutical disposal on pro-environmental disinfectant use among Chinese residents.docx |
| title_full | Table 1_Potential spillover effect of eco-directed pharmaceutical disposal on pro-environmental disinfectant use among Chinese residents.docx |
| title_fullStr | Table 1_Potential spillover effect of eco-directed pharmaceutical disposal on pro-environmental disinfectant use among Chinese residents.docx |
| title_full_unstemmed | Table 1_Potential spillover effect of eco-directed pharmaceutical disposal on pro-environmental disinfectant use among Chinese residents.docx |
| title_short | Table 1_Potential spillover effect of eco-directed pharmaceutical disposal on pro-environmental disinfectant use among Chinese residents.docx |
| title_sort | Table 1_Potential spillover effect of eco-directed pharmaceutical disposal on pro-environmental disinfectant use among Chinese residents.docx |
| topic | Public Health and Health Services not elsewhere classified disinfection ecopharmacovigilance emerging contaminants environmental spillover knowledge-attitude-practice pharmaceutical emerging contaminants |