Deletion of <i>Scarb1</i> in LysM-Cre expressing cells does not affect microarchitecture of cancellous bone in male mice.

<p>Micro-CT analysis of cancellous bone architecture in 6-month-old males. (A) Trabecular number, (B) trabecular thickness, and (C) trabecular separation of vertebral cancellous bone. (D) Trabecular number, (E) trabecular thickness, and (F) trabecular separation of femoral cancellous bone [WT...

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Bibliografiset tiedot
Päätekijä:	Michela Palmieri (12316894) (author)
Muut tekijät:	Teenamol E. Joseph (12316897) (author), Horacio Gomez-Acevedo (507697) (author), Ha-Neui Kim (14907815) (author), Stavros C. Manolagas (12316900) (author), Charles A. O’Brien (10776770) (author), Elena Ambrogini (12316903) (author)
Julkaistu:	2025
Aiheet:	Biochemistry Cell Biology Genetics Physiology Ecology Immunology Developmental Biology Cancer Chemical Sciences not elsewhere classified multiple cell types low density lipoproteins high fat diet high density lipoproteins e06 igm – containing oxidized phospholipids cell surface receptor l </ sup induced bone loss increasing bone formation bone mineral density affect bone mass knockout mice (< abundant scavenger receptor oxpls could exert investigated whether pc div >< p osteoblast lineage cells adverse skeletal effects cre expressing cells wt ), osx1 scarb1 ), encoded cre transgenic mice lysm </ sup fl </ sup scavenger receptor scarb1 </ >< sup skeletal analysis osteoblast progenitors cortical bone osteoblastic cells myeloid cells negative effects differentiating effects adult mice oxldl ), recognizes pc oxpls ). osteoblasts derived natural antibody including osteoblasts ct analysis 6 months
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Yhteenveto:	<p>Micro-CT analysis of cancellous bone architecture in 6-month-old males. (A) Trabecular number, (B) trabecular thickness, and (C) trabecular separation of vertebral cancellous bone. (D) Trabecular number, (E) trabecular thickness, and (F) trabecular separation of femoral cancellous bone [WT n = 14; <i>Scarb1</i><sup>fl/fl</sup> n = 14; LysM-Cre n = 11; <i>Scarb1</i><sup>ΔLysM</sup> n = 16]. Data are shown as mean and standard deviation. Data analyzed by 2-way ANOVA; the p-values were adjusted using the Tukey’s pairwise comparison procedure. Tb, trabecular.</p> <p>(TIF)</p>

Deletion of <i>Scarb1</i> in LysM-Cre expressing cells does not affect microarchitecture of cancellous bone in male mice.

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