Acute and convalescent serological data from Thai cohorts used in this analyses, colored by true infections status and prediction of infection during model testing.

Acute and convalescent serological data from Thai cohorts used in this analyses, colored by true infections status and prediction of infection during model testing.

<p><b>a)</b> Geometric mean titers of a haemagglutination inhibition assay (GM HAI) for all four serotypes of dengue virus. <b>b)</b> Immunoglobulin M (IgM) <b>c)</b> Immunoglobulin G (IgG) <b>d)</b> Ratio of IgM to IgG at both acute and convales...

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Main Author: Marco Hamins-Puértolas (15238661) (author)
Other Authors: Darunee Buddhari (625855) (author), Henrik Salje (589157) (author), Angkana T. Huang (12262139) (author), Taweewun Hunsawong (798675) (author), Derek A.T. Cummings (14971341) (author), Stefan Fernandez (146590) (author), Aaron Farmer (4288318) (author), Surachai Kaewhiran (22683535) (author), Direk Khampaen (22683538) (author), Anon Srikiatkhachorn (110184) (author), Sopon Iamsirithaworn (260152) (author), Adam Waickman (118668) (author), Stephen J. Thomas (7105673) (author), Timothy Endy (150971) (author), Alan L. Rothman (6835178) (author), Kathryn B. Anderson (6835166) (author), Isabel Rodriguez-Barraquer (233670) (author)
Published: 2025
Subjects:
Medicine
Biotechnology
Ecology
Immunology
Cancer
Science Policy
Infectious Diseases
Virology
Computational Biology
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
since many cases
linked immunosorbent assay
independently utilize information
hemagglutination inhibition assay
globe &# 8217
currently implemented cut
convalescent serum collected
87 &# 8211
82 &# 8211
real world data
multiple serological assays
infer infection events
generate finalized interpretations
bayesian mixture model
prior standard interpretations
pcr confirmed infections
jointly model data
gold standard ).
f1 scores ).
hai data consistently
direct detection methods
gold standard
f1 scores
infection detection
eia ).
including data
individual assays
new model
igm data
whether individuals
transmission potential
results provide
recently experienced
provide insight
probabilistic framework
population living
point approaches
pathogen systems
kamphaeng phet
interpreting results
incorporating igg
important role
higher accuracy
first test
diagnostic process
creating uncertainty
combined metric
already half
677 pairs
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