Related to Fig 2. CD24-Fc treatment reduces HIV-1 pathogenesis during cART.

<p>Humanized mice were infected and treated as in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1012826#ppat.1012826.g001" target="_blank">Fig 1A</a> and splenocytes were analyzed by FACS on termination. (A) Representative FACS plot...

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Glavni avtor: Guangming Li (607051) (author)
Drugi avtorji: Jianping Ma (816945) (author), Haisheng Yu (607054) (author), Ourania Tsahouridis (11909960) (author), Yaoxian Lou (22022137) (author), Xiuting He (11909963) (author), Masaya Funaki (11909966) (author), Pan Zheng (25267) (author), Yang Liu (4829) (author), Lishan Su (33524) (author)
Izdano: 2025
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Izvleček:<p>Humanized mice were infected and treated as in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1012826#ppat.1012826.g001" target="_blank">Fig 1A</a> and splenocytes were analyzed by FACS on termination. (A) Representative FACS plots show the frequency of CD4+ or CD8 + T cell in CD3 + cells. (B) Summary graphs show the number of hCD45 + cell, CD4 + T, CD8 + T cell and CD3- cell per spleen. (C) Representative FACS for the expression of HLA-DR and CD38 expression in CD8 T cells. (D) Representative FACS for the expression of CD45RA and CCR7 expression in CD8 T cells. (E) Summary graphs show the frequency of PD-1 + cell in central memory or effector memory CD8 T cells. (F) Summary graphs show the frequency of CXCR5 + cell in total CD8 T cells. Bar represents mean value.</p> <p>(TIF)</p>