Role of MPL36 on the pathogenesis of Leptospira interrogans.

(A) Ability of leptospires strains to adhere to MDCK epithelial cells. Manilae WT, Δmpl36, and Δmpl36+ strains were incubated with immobilized MDCK cells for one hour at 37°C and adhesion assessed by immunofluorescence. Data repre...

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محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Weinan Zhu (1640407) (author)
مؤلفون آخرون:	Felipe J. Passalia (11755241) (author), Camila Hamond (5745839) (author), Cecília M. Abe (16641688) (author), Albert I. Ko (90448) (author), Angela S. Barbosa (8989760) (author), Elsio A. Wunder Jr. (10105020) (author)
منشور في:	2023
الموضوعات:	Biochemistry Medicine Microbiology Cell Biology Molecular Biology Biotechnology Immunology Infectious Diseases Plant Biology Virology significant attenuated phenotype novel potential candidate div >< p using koch ’ terminal sporulation related omps ), particularly using recombinant mpl36 mpl36 characterization contributes using recombinant protein play crucial roles pathogenic spirochetes belonging important virulence factor mpl36 ), terminal region pathogen ’ mpl36 </ worldwide distribution virulence mechanisms results confirmed rare lipoprotein pathogen dissemination molecular postulates major plasminogen lysine residues leptospira </ improve diagnostic host tissues high plasminogen hamster model exposed regions expanding field essential role degrade fibrinogen decreased capacity data indicates convert bound bound plasmin bacterial pathogens active plasmin
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Role of MPL36 on the pathogenesis of <i>Leptospira interrogans</i>.

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