Table 2_Targeting the KLF5/PI3K/AKT axis as a therapeutic strategy to overcome neoadjuvant chemoresistance in colorectal cancer.csv

Table 2_Targeting the KLF5/PI3K/AKT axis as a therapeutic strategy to overcome neoadjuvant chemoresistance in colorectal cancer.csv

Background<p>Oxaliplatin-based neoadjuvant chemotherapy (NAC) is the standard treatment for advanced colorectal cancer (CRC), yet resistance to NAC poses a significant clinical challenge.</p>Methods<p>To investigate the mechanisms of chemoresistance, we analyzed single-cell RNA seq...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Meiling Gao (6175109) (author)
مؤلفون آخرون: Jiahao Qian (21717053) (author), Ping Xia (220386) (author), Wancheng Liu (7213538) (author), Yunjia Jiang (18806562) (author), Yuchang Xia (21717056) (author), Xin Yao (130614) (author), Qingqing Jiao (7496864) (author), Minggang Wei (13014378) (author)
منشور في: 2025
الموضوعات:
Genetic Immunology
colorectal cancer
oxaliplatin resistance
KLF5
GDC-0941
neoadjuvant chemotherapy
PI3K/Akt pathway
chemoresistance
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