Immunohistochemical analysis of testis sections (Olympus BX51, Tokyo, Japan. X40: Scale bar; 100 µm).

<p>Levels of autophagy markers in the testes of control and treated group. EVs treatment ameliorated expression of Beclin-1, P62, and LC3-2 levels in the testes of cisplatin-induced rats. Avidin-biotin peroxidase technique.</p>

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Bibliographic Details
Main Author:	Halime Tozak Yıldız (21238185) (author)
Other Authors:	Kübra Tuğçe Kalkan (21238188) (author), Numan Baydilli (4656673) (author), Zeynep Burçin Gönen (12282920) (author), Özge Cengiz Mat (21238191) (author), Eda Köseoğlu (21238194) (author), Gözde Özge Önder (21238197) (author), Arzu Yay (502589) (author)
Published:	2025
Subjects:	Biochemistry Cell Biology Molecular Biology Physiology Biotechnology Developmental Biology Marine Biology Cancer Chemical Sciences not elsewhere classified two male rats structural changes led promising therapeutic strategy modulating oxidative stress linked immunosorbent assay lc3 – 2 induces significant gonadotoxicity increased oxidative stress determined via enzyme assessed via hematoxylin 8 ): control testicular toxicity model induced testicular damage reduced germinal epithelium oxidative stress markers induced reproductive toxicity preserving testicular function single intraperitoneal dose antioxidant activities increased sod ), catalase 001 ), suggesting xlink "> cisplatin mda levels decreased testicular function xlink "> single dose decreased activities testicular histoarchitecture reproductive health mda ), 001 ), autophagy markers evs reduced various cancers underlying mechanisms study investigates steroidogenic factors sperm parameters sperm motility six day seminiferous tubules randomly divided protective effect negative effects mitigate cisplatin localized applications kg cisplatin infertility due including motility immunohistochemical analysis hormone levels hormonal imbalances glutathione peroxidase four groups first day findings suggest extracellular vesicles eosin staining elisa ). elevated levels dosing regimens day eight alongside downregulation adverse effects 001 ).
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Immunohistochemical analysis of testis sections (Olympus BX51, Tokyo, Japan. X40: Scale bar; 100 µm).

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