Therapeutic effects of miR-150-5p inhibition on ox-LDL-induced pyroptosis in RAW264.7 macrophages.

<p>(A) Cell viability measured by CCK-8 assay. (B) Cytotoxicity assessed by LDH release into culture media. (C) TUNEL staining showing DNA fragmentation (red) with DAPI counterstain (blue). Scale bar: 100 μm. (D-E) Western blot analysis of pyroptosis-related proteins (cleaved GSDMD, NLRP3, ASC...

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Main Author:	Ping-yu Cai (12389929) (author)
Other Authors:	Mei-mei Li (11067777) (author), Shu-han Chen (22453480) (author), Yan-li Zheng (12389923) (author), Jun Li (6494) (author), De-hong Huang (22453483) (author), Jing-ru Du (12389932) (author), Hui-li Lin (22453486) (author)
Published:	2025
Subjects:	Biophysics Biochemistry Cell Biology Genetics Molecular Biology Developmental Biology Marine Biology Cancer Infectious Diseases Virology Biological Sciences not elsewhere classified study advances understanding improving cell viability decreasing ldh levels foxo3a knockdown weakened mouse vascular tissue inhibitor upregulated foxo3a enhancing macrophage pyroptosis xlink "> exosomes 5p regulated foxo3a 5p target genes atherosclerosis </ p foxo3a regulated xlink "> tissue exosomes target interactions downstream genes 5p inhibitor inhibitor ’ 5p promotes 5p inhibitors vivo efficacy pathophysiological significance n ). mediated pyroptosis masson staining induced raw264 functional mechanisms evaluated using 7 injury
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Therapeutic effects of miR-150-5p inhibition on ox-LDL-induced pyroptosis in RAW264.7 macrophages.

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